149647-78-9    
 
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CAS 149647-78-9 Vorinostat | Products & Prices & Suppliersts

It is the first HDAC inhibitor approved by the US Food and Drug Administration (FDA) for the treatment of cutaneous T-cell lymphoma (CTCL) with significant skin involvement that is still progressing, resistant or relapsing after two systemic regimens. On October 6, 2006, the US Food and Drug Administration (FDA) have approved vorinostat capsules (vorinostat) for the treatment of skin cancer drugs. The drug is the first novel type of anti-cancer drugs of histone deacetylase inhibitor devel.

ldentification

Cas NO.: 149647-78-9
CID: 5311
Mw: 264.3202
MF: C14H20N2O3
Name:Vorinostat (Related Reference)
Synonyms: CS-1949; M344; N-Hydroxy-N'-phenyloctanediamide; Octanediamide, N1-hydroxy-N8-phenyl-; Octanediamide, N-hydroxy-N-phenyl-; SAHA; SAHA cpd; SAHA, N-Hydroxy-Nphenyloctanediamide, Zolinza;
EINECS: 1308068-626-2

Safety Data

[Risk Codes]
[Safety Statements]
Hazard Symbols:

Properties

Appearance:White Crystalline Solid
Molecular Weight:264.3202
Density:1.174
Boiling Point:°Cat760mmHg
Melting Point:161-162°C
Flash Point:°C
Storage Temperature:-20°C
Refractive index:1.566
Solubility:Soluble in ethanol (0.25 mg/ml), DMSO & DMF (20 mg/ml)
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Octanediamide,N1-hydroxy-N8-phenyl-
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Question & Answer
Can the anti-cancer drug Vorinostat really treat HPV infection? When asked about this type of question, friends who are not very familiar with this drug often cannot give a corresponding answer. Of course, to answer this question well, it is necessary to have a ce.. Mar 01 2023
What is the efficacy of Vorinostat and its potential applications? Vorinostat is a group of histone deacetylase (HDAC) inhibitors that work by inducing cell differentiation, blocking the cell cycle, and inducing cell regulation. It is used to treat cutaneous T-cell l.. Jan 27 2023
What are the instructions for Vorinostat? Background and overview[1][2] Vorinostat (vorinostat) is a deacetylase inhibitor (histone deacetylase inhibitor, HDACI). It can upregulate tumor suppressor genes by interfering with the activity of de.. Oct 23 2020
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