CAS 50-35-1 Thalidomide | Products & Prices & Suppliersts

Thalidomide (CAS 50-35-1) is a white to off-white crystalline powder that is sparingly soluble in water and slightly soluble in ethanol. It has a basic structure consisting of a phthalimide ring with a glutarimide side chain. Thalidomide exhibits physical properties such as a melting point of 269-271°C and a molecular weight of 258.22 g/mol. It is chemically stable under normal conditions and does not undergo significant decomposition or degradation.

Applicable Fields

Thalidomide has various applications in the medical field:

Cancer Treatment: Thalidomide is used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. Its mechanism of action involves inhibiting the growth of blood vessels that supply nutrients to tumors, thereby reducing their size and preventing their spread.

Immunomodulation: Thalidomide is also utilized for its immunomodulatory properties. It can modulate the immune system by affecting the production of certain cytokines and inhibiting the activity of inflammatory cells. This makes it useful in the treatment of conditions such as leprosy and certain autoimmune diseases.

Thalidomide is strictly regulated due to its history of causing birth defects when taken during pregnancy. It is only prescribed under strict conditions and with appropriate precautions to prevent fetal exposure.

Storage Conditions

Store in a cool, dry place.

ldentification

: Cas NO.: 50-35-1; CID: 5426; Mw: 258.233; MF: C13H10N2O4; Name:Thalidomide (Related Reference); Synonyms: (+/-)-N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE; (+/-)-THALIDOMIDE; 3-PHTHALIMIDOGLUTARIMIDE; N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE; N-PHTHALOLYLGLUTAMIMIDE; α-Phthalimidoglutarimide;; EINECS: 200-031-1

Safety Data

: [Risk Codes]; [Safety Statements]; Hazard Symbols:

Properties

: Molecular Weight:258.233; Density:1.2944 (rough estimate); Boiling Point:401.48°C (rough estimate); Melting Point:269-271°C; Storage Temperature:Keep in dark place,Sealed in dry,Room Temperature; Solubility:less than 1 mg/mL at 72 °F (NTP, 1992); Stability:Stable under recommended storage conditions.; More Properties>>

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Question & Answer

: How did Thalidomide transform from a devil to an angel in treating rheumatism upon its relaunch? Thalidomide (THD), also known as "Thalidomide", was delisted due to a well-known shameful history. However, the medical community later discovered that in addition to its teratogenic effects (pregnan.. Oct 06 2022; What was the Counterattack of Thalidomide? The Thalidomide incident is the most famous drug-induced injury incident in the history of world drugs and a milestone in the history of world pharmacovigilance. It has an important role in promoting.. Sep 25 2022; What are the side effects of Thalidomide? Thalidomide (English: Thalidomide), also known as thalidomide, thalidomide, thalidomide, and Thado, is a drug with central inhibitory effects discovered during the development of antibacterial drugs. .. Nov 03 2021