51-41-2    
 
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CAS 51-41-2 Norepinephrine | Products & Prices & Suppliersts

Norepinephrine (CAS 51-41-2) is a neurotransmitter and hormone that plays a crucial role in the body's response to stress. It is a catecholamine compound with a chemical structure similar to adrenaline. Norepinephrine is a white crystalline powder that is soluble in water. It has a molecular weight of 169.18 g/mol and a melting point of 220°C. The compound is stable under normal conditions and is both odorless and tasteless.

Applicable Fields
Norepinephrine has various applications in the medical field:
- Cardiovascular Medicine: Norepinephrine is used as a vasopressor to increase blood pressure in cases of severe hypotension or shock. It acts by constricting blood vessels, thereby increasing peripheral resistance and improving blood flow to vital organs.
- Neurology: Norepinephrine is involved in the regulation of mood, attention, and arousal. It is used in the treatment of certain neurological disorders, such as attention deficit hyperactivity disorder (ADHD) and depression.
- Anesthesiology: Norepinephrine is used during anesthesia to maintain blood pressure and prevent hypotension. It helps to counteract the vasodilatory effects of anesthetics.

Mechanism of Action
Norepinephrine acts by binding to adrenergic receptors located on the surface of target cells. It primarily activates alpha-1 and beta-1 adrenergic receptors, leading to various physiological responses. Activation of alpha-1 receptors causes vasoconstriction, while activation of beta-1 receptors increases heart rate and contractility. These actions result in increased blood pressure and improved cardiac output.

Storage Conditions
Store in a cool, dry place.

ldentification

Cas NO.: 51-41-2
CID: 439260
Mw: 169.18
MF: C8H11NO3
Name:Norepinephrine (Related Reference)
Synonyms: (−)-Norepinephrine; (-)-(R)-Norepinephrine; (-)-a-(Aminomethyl)protocatechuyl alcohol; (-)-alpha-(aminomethyl)protocatechuylalcohol; (-)-noradrec; (-)-NORADRENALINE; (-)-norepinephrine; (R)-(-)-norepinephrine;
EINECS: 205-337-9; 200-096-6

Safety Data

[Risk Codes] R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed
[Safety Statements] S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) S36/37:Wear suitable protective clothing and gloves S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Hazard Symbols: HazardClass: 6.1

Properties

Appearance:crystalline
Molecular Weight:169.18
Density:1.397
Boiling Point:442.6 °C at 760 mmHg
Melting Point:220℃
Flash Point:221.5 °C
Alpha:D25 -37.3° (c = 5 in water with 1 equiv HCl)
Storage Temperature:2-8°C
Refractive index:1.66
Solubility:

Stability:Stable, but may be light-sensitive. Incompatible with acids, bases, oxidizing agents. Store at -20C.
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Question & Answer
What is the role of Norepinephrine in the body? Norepinephrine, also known as noradrenaline, serves as both a neurotransmitter and a hormone. Its physiological effects are mediated by adrenergic receptors, α1, α2, and β. Drugs can activate or i.. Jul 27 2024
What is Norepinephrine and its Role in the Body? Norepinephrine (NE or NA) is a substance formed by removing the N-methyl group from adrenaline, and it belongs to the chemical structure of catecholamines. It serves as a neurotransmitter and is prim.. Mar 20 2023
What are the Roles of Noradrenaline and Adrenaline in the Body? Discovery Adrenaline, also known as epinephrine, was isolated from the adrenal gland of oxen by Jokichi Takamine and his assistant Keizo Uenaka in 1900. Noradrenaline, on the other hand, was identifi.. Jun 23 2022
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