Lovastatin, with the chemical formula C24H36O5, has the CAS number 75330-75-5. It is a white to off-white crystalline powder with no distinct odor. Lovastatin is a naturally occurring statin that is derived from a fermentation product of Aspergillus terreus. Its basic structure consists of a lactone ring attached to a dihydroxyheptanoic acid side chain. This compound is practically insoluble in water, but soluble in organic solvents such as ethanol and methanol. Lovastatin is classified as a prescription medication and should be used under the guidance of a healthcare professional. It is important to follow the safety information provided by the manufacturer or healthcare provider when handling and using this chemical.
Applicable Fields
Cholesterol-lowering agent: Lovastatin is primarily used as a cholesterol-lowering agent. It works by inhibiting the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the body. By reducing cholesterol levels, lovastatin helps to prevent the buildup of plaque in the arteries and lowers the risk of heart disease.
Antifungal agent: In addition to its cholesterol-lowering properties, lovastatin also exhibits antifungal activity. It has been used in the treatment of fungal infections, particularly those caused by Aspergillus species. The mechanism of action in this context involves the inhibition of fungal cell growth and the disruption of fungal cell membranes.
Storage
Conditions: Store in a cool and dry place.