75330-75-5    
 
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CAS 75330-75-5 Lovastatin | Products & Prices & Suppliersts

Lovastatin, with the chemical formula C24H36O5, has the CAS number 75330-75-5. It is a white to off-white crystalline powder with no distinct odor. Lovastatin is a naturally occurring statin that is derived from a fermentation product of Aspergillus terreus. Its basic structure consists of a lactone ring attached to a dihydroxyheptanoic acid side chain. This compound is practically insoluble in water, but soluble in organic solvents such as ethanol and methanol. Lovastatin is classified as a prescription medication and should be used under the guidance of a healthcare professional. It is important to follow the safety information provided by the manufacturer or healthcare provider when handling and using this chemical.

Applicable Fields

Cholesterol-lowering agent: Lovastatin is primarily used as a cholesterol-lowering agent. It works by inhibiting the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the body. By reducing cholesterol levels, lovastatin helps to prevent the buildup of plaque in the arteries and lowers the risk of heart disease.

Antifungal agent: In addition to its cholesterol-lowering properties, lovastatin also exhibits antifungal activity. It has been used in the treatment of fungal infections, particularly those caused by Aspergillus species. The mechanism of action in this context involves the inhibition of fungal cell growth and the disruption of fungal cell membranes.

Storage

Conditions: Store in a cool and dry place.

ldentification

Cas NO.: 75330-75-5
CID: 53232
Mw: 404.547
MF: C24H36O5
Name:Lovastatin (Related Reference)
Synonyms: (+)-Mevinolin; (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl (S)-2-Methylbutyrate;
EINECS: 616-212-7

Safety Data

[Risk Codes] R36/37/38:Irritating to eyes, respiratory system and skin
[Safety Statements] S22:Do not breathe dust S24/25:Avoid contact with skin and eyes
Hazard Symbols: HazardClass: 9

Properties

Appearance:White solid
Molecular Weight:404.547
Density:1.12
Boiling Point:559.2 oC at 760 mmHg
Melting Point:175℃
Flash Point:185.3 oC
Storage Temperature:2-8°C
Refractive index:320 ° (C=0.5, CH3CN)
Solubility:0.0004 mg/mL at 25 oC
Stability:Stable under recommended storage conditions.
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Question & Answer
What are the potential risks and side effects of Lovastatin? Lovastatin is a novel fully synthetic hydroxymethylglutaryl-CoA reductase inhibitor and is one of the most effective lipid-lowering drugs currently available. Pharmacology and Toxicology Lovastatin c.. Jun 16 2024
How can we effectively use Lovastatin? Lovastatin is a commonly used medication, widely used to lower cholesterol and prevent cardiovascular diseases. So, how can we effectively use Lovastatin? This article will explore some methods and p.. Oct 25 2023
How was Lovastatin Discovered and Synthesized? In August 1979, shortly after Shoujiro Endo published his paper on monacolin K, researchers at Merck Pharmaceuticals announced that they had also isolated a compound called mevinolin from the culture .. Jan 03 2023
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