Azelastine hydrochloride, with the chemical formula C22H24ClN3O, has the CAS number 79307-93-0. It is a white or almost white crystalline powder. Azelastine hydrochloride has no characteristic odor. Its basic structure consists of a hydrochloride salt of azelastine, which is an antihistamine. This compound is freely soluble in water and in methanol, slightly soluble in ethanol, and practically insoluble in ether. Azelastine hydrochloride is stable under normal conditions of use and storage. It is not reactive with common materials and is not considered to be a fire hazard. However, it may be irritating to the eyes, skin, and respiratory system. It is recommended to handle this compound with care and use appropriate protective measures.
Applicable Fields
Allergy Treatment: Azelastine hydrochloride is commonly used in the treatment of allergies. Its mechanism of action involves blocking the effects of histamine, a substance in the body that causes allergic symptoms such as itching, sneezing, and runny nose. Azelastine hydrochloride helps relieve these symptoms by reducing the release of histamine and other chemicals in the body.
Nasal Congestion: This compound is also used to relieve nasal congestion associated with seasonal allergies and allergic rhinitis. It works by reducing the swelling and inflammation in the nasal passages, allowing for easier breathing and relieving congestion.
Storage
Conditions: Store in a cool and dry place.