79902-63-9    
 
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CAS 79902-63-9 Simvastatin | Products & Prices & Suppliersts

Simvastatin, with the chemical formula C25H38O5, has the CAS number 79902-63-9. It is a white to off-white, crystalline powder with no distinct odor. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. Its basic structure consists of a lactone ring attached to a substituted hexahydroindole ring. This compound is practically insoluble in water, but freely soluble in chloroform, methanol, and ethanol. Simvastatin is a prescription medication used to lower cholesterol and triglyceride levels in the blood. It is also used to reduce the risk of heart attack, stroke, and other cardiovascular events in individuals with high cholesterol levels. Safety information indicates that Simvastatin may cause side effects such as muscle pain, liver problems, and digestive issues. It should be used with caution in patients with liver disease or who consume large amounts of alcohol. Simvastatin should not be taken during pregnancy or while breastfeeding. It is important to consult a healthcare professional before starting or stopping Simvastatin treatment.

Applicable Fields

Cardiovascular Health: Simvastatin is primarily used in the field of cardiovascular health. Its purpose is to lower cholesterol and triglyceride levels in the blood, thereby reducing the risk of heart disease, heart attack, stroke, and other cardiovascular events. The mechanism of action of Simvastatin involves inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the body. By inhibiting this enzyme, Simvastatin helps to decrease the production of cholesterol and increase the clearance of LDL cholesterol from the bloodstream.

Storage

ConditionsStore in a cool and dry place.

ldentification

Cas NO.: 79902-63-9
CID: 54454
Mw: 418.56622
MF: C25H38O5
Name:Simvastatin (Related Reference)
Synonyms: (1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste;
EINECS: 404-520-2

Safety Data

[Risk Codes] R36/37/38:Irritating to eyes, respiratory system and skin
[Safety Statements]
Hazard Symbols: HazardClass: 9

Properties

Appearance:white
Molecular Weight:418.56622
Density:1.11 g/cm3
Boiling Point:564.9 °C at 760 mmHg
Melting Point:139 °C
Flash Point:184.8 °C
Alpha:D25 +292° (c = 0.5% in acetonitrile)
Storage Temperature:0-6°C
Refractive index:1.53
Solubility:H2O: Insoluble ;DMSO: ≥20mg/mL
Stability:Simvastatin tablets should be stored at 5-30 deg C. When stored under these conditions, the tablets are stable for 24 months after the date of manufacture. The fixed-combination preparation containing simvastatin and ezetimibe should be stored in well-closed containers at 20-25 deg C.
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Question & Answer
What are the potential side effects of simvastatin and how can they be managed? Introduction Simvastatin is a prescription drug available in tablet and suspension forms, both taken orally. It is known as Zocor as a brand-name drug and is also available as a generic medication. Si.. Aug 31 2024
What is Simvastatin and how does it work? Simvastatin, also known by its brand name "Zocor," is an oral medication used to lower blood lipid levels. It can be used in conjunction with exercise, dietary control, and weight loss to prevent lipi.. May 13 2023
What are the benefits and uses of Simvastatin? Simvastatin offers a high value for its price and is commonly used in clinical medicine. It has excellent effects, especially for individuals with high blood lipids, as it effectively lowers blood lip.. Nov 01 2022
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