Simvastatin, with the chemical formula C25H38O5, has the CAS number 79902-63-9. It is a white to off-white, crystalline powder with no distinct odor. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. Its basic structure consists of a lactone ring attached to a substituted hexahydroindole ring. This compound is practically insoluble in water, but freely soluble in chloroform, methanol, and ethanol. Simvastatin is a prescription medication used to lower cholesterol and triglyceride levels in the blood. It is also used to reduce the risk of heart attack, stroke, and other cardiovascular events in individuals with high cholesterol levels. Safety information indicates that Simvastatin may cause side effects such as muscle pain, liver problems, and digestive issues. It should be used with caution in patients with liver disease or who consume large amounts of alcohol. Simvastatin should not be taken during pregnancy or while breastfeeding. It is important to consult a healthcare professional before starting or stopping Simvastatin treatment.
Applicable Fields
Cardiovascular Health: Simvastatin is primarily used in the field of cardiovascular health. Its purpose is to lower cholesterol and triglyceride levels in the blood, thereby reducing the risk of heart disease, heart attack, stroke, and other cardiovascular events. The mechanism of action of Simvastatin involves inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the body. By inhibiting this enzyme, Simvastatin helps to decrease the production of cholesterol and increase the clearance of LDL cholesterol from the bloodstream.
Storage
ConditionsStore in a cool and dry place.