Fmoc-O-benzyl-L-serine, with the chemical formula C34H31NO5, has the CAS number 83792-48-7. It appears as a white to off-white powder with no distinct odor. The basic structure of Fmoc-O-benzyl-L-serine consists of a serine molecule with an Fmoc (9-fluorenylmethoxycarbonyl) protecting group attached to the hydroxyl group and a benzyl group attached to the amino group. This compound is sparingly soluble in water, but soluble in organic solvents such as methanol and dimethyl sulfoxide. Fmoc-O-benzyl-L-serine is a stable compound under normal conditions.
Applicable Fields
Peptide synthesis: Fmoc-O-benzyl-L-serine is commonly used in peptide synthesis as a protected amino acid. Its purpose in this field is to serve as a building block for the synthesis of peptides and proteins. The mechanism of action in peptide synthesis involves the selective removal of the Fmoc protecting group under basic conditions, allowing for the subsequent coupling of the amino acid to other amino acids.
Drug development: Fmoc-O-benzyl-L-serine can also be used in drug development and pharmaceutical research. Its purpose in this field is to modify the properties of drug molecules, such as improving their solubility or stability. The mechanism of action in drug development involves the incorporation of Fmoc-O-benzyl-L-serine into the drug molecule, which can affect its pharmacokinetics and therapeutic efficacy.
Storage
Conditions: Store in a cool and dry place.