Guaiacol (CAS 90-05-1) is a colorless to pale yellow liquid with a characteristic smoky odor. It has a basic structure consisting of a benzene ring with a hydroxyl group (-OH) and a methoxy group (-OCH3) attached. Guaiacol is soluble in organic solvents such as ethanol, ether, and chloroform, but it is only slightly soluble in water. The physical properties of guaiacol include a boiling point of 205-207°C, a melting point of 28-30°C, and a density of 1.129 g/cm3.
Applicable Fields
Pharmaceutical Industry: Guaiacol is commonly used in the pharmaceutical industry as a starting material for the synthesis of various drugs. It serves as a precursor for the production of compounds such as vanillin, which is used as a flavoring agent, and guaifenesin, which is an expectorant.
Flavor and Fragrance Industry: Guaiacol is also utilized in the flavor and fragrance industry. It imparts a smoky, phenolic aroma and is often used in the production of flavors such as smoked meats, coffee, and whiskey.
Mechanism of Action
The mechanism of action of guaiacol depends on its specific application. In the pharmaceutical industry, it acts as a precursor for the synthesis of other compounds, providing the necessary functional groups for drug activity. In the flavor and fragrance industry, guaiacol contributes to the overall aroma profile of products, enhancing their sensory appeal.
Storage Conditions
Store in a cool, dry place.