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2,6-Dibromopyridine

CAS：626-05-1
MW:236.89
MF：C5H3Br2N

2,6-Dibromopyridine, with the chemical formula C5H3Br2N and CAS registry number 626-05-1, is a compound known for its applications in various chemical processes. This yellow crystalline solid is characterized by its two bromine atoms attached to the pyridine ring. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and dyes. 2,6-Dibromopyridine is also used as a reagent in organic synthesis, offering a versatile platform for the introduction of bromine atoms into different molecules. It is important to handle this compound with caution, as it is toxic and may cause skin and eye irritation. Overall, 2,6-Dibromopyridine plays a crucial role in the development of various chemical compounds and has a wide range of applications in the field of chemistry.

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Names and ldentifier
Properties
Use and Manufacturing
Msds
Other Information
Computational chemical data
Related Questions
Realated Product Infomation

1. Names and Identifiers

1.1 Name: 2,6-Dibromopyridine

1.2 Synonyms: 2,4-dibroMo-6-nitropyridine; 2,6-dibromo-pyridin; NSC 613; Pyridine, 2,6-dibromo-;

1.3 CAS No.: 626-05-1

1.4 CID: 12274

1.5 EINECS: 210-926-9

1.6 Molecular Formula: C5H3Br2N

1.7 Inchi: InChI=1S/C5H3Br2N/c6-4-2-1-3-5(7)8-4/h1-3H

1.8 InChkey: FEYDZHNIIMENOB-UHFFFAOYSA-N

1.9 Canonical Smiles: C1=CC(=NC(=C1)Br)Br

1.10 Isomers Smiles: C1=CC(=NC(=C1)Br)Br

2. Properties

2.1 Appearance: Light-yellow Solid

2.2 Storage: Ambient temperatures.

2.3 Chemical Properties: White to light yellow crystalline powder

2.4 Color/Form: White to gray or buff

2.5 pKa: -3.65±0.10(Predicted)

2.6 Water Solubility: Chloroform (Slightly), Methanol (Slightly)

2.7 Stability: Stable under normal temperatures and pressures.

2.8 StorageTemp: Keep in dark place,Sealed in dry,Room Temperature

3. Use and Manufacturing

3.1 Description

2,6-Dibromopyridine, with the chemical formula C5H3Br2N, has the CAS number 626-05-1. It appears as a yellow to brown solid with a strong odor. The basic structure of 2,6-Dibromopyridine consists of a pyridine ring with two bromine atoms attached at the 2 and 6 positions. This compound is sparingly soluble in water. Safety information indicates that 2,6-Dibromopyridine may cause irritation to the skin, eyes, and respiratory system. It is important to avoid ingestion and inhalation of this chemical. In case of contact, immediate medical attention should be sought. Proper protective measures should be taken when handling 2,6-Dibromopyridine to ensure safety.

Applicable Fields

Pesticides: 2,6-Dibromopyridine is used as an intermediate in the synthesis of various pesticides. Its purpose in this field involves its ability to act as a building block for the production of effective pest control agents. The mechanism of action in pesticides may vary depending on the specific compound being synthesized.

Pharmaceuticals: This compound is also utilized in the pharmaceutical industry. It can serve as a starting material for the synthesis of certain drugs. The mechanism of action in pharmaceuticals depends on the specific drug being produced.

Storage

Conditions: Store in a cool and dry place.

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3.2 Purification Methods: Purify 2,6-dibromopyridine by steam distillation, then recrystallise it twice from EtOH. It does not form an HgCl2 salt. [den Hertog & Wibaut Recl Trav Chim Pays Bas 51 381 1932, Beilstein 20/5 V 435.] 2,6-Dibromopyridine Preparation Products And Raw materials Preparation Products

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4. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 2

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/\u2026 P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

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5. Synthesis Route

626-05-1Total: 10 Synthesis Route

694-59-7 102 Suppliers

626-05-1 242 Suppliers

462-08-8 179 Suppliers

626-05-1 242 Suppliers

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6. Precursor and Product

precursor:

7789-69-7

462-08-8

2402-78-0

873383-11-0

110-86-1

7789-60-8

109-04-6

694-59-7

39856-57-0

25373-69-7

product:

2402-78-0

581-47-5

2408-70-0

108-48-5

6231-18-1

109-04-6

4645-11-8

2530-26-9

141-86-6

5140-72-7

7. Computed Properties

Molecular Weight：236.89g/mol
Molecular Formula：C₅H₃Br₂N
Compound Is Canonicalized：True
Exact Mass：2.9
XLogP3-AA：236.86117
Monoisotopic Mass：234.86322
Complexity：68.8
Rotatable Bond Count：0
Hydrogen Bond Donor Count：0
Hydrogen Bond Acceptor Count：1
Topological Polar Surface Area：12.9
Heavy Atom Count：：8
Defined Atom Stereocenter Count：0
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：1
CACTVS Substructure Key Fingerprint：AAADcQBiAAAAGAAAAAAAAAAAAAAAAAAAAAAsAAAAAAAAAAABgAAAHABAAAABOACBEgAwgJIIEACgACBiRACCgCAhAiQImCAwZLgIIOLAkZGEIAhggADIyhYQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

8.Other Information

Usage: 2,6-Dibromopyridine is used as a tridentate chelating ligand and in the formation of macrocycles containing the terpyridine moiety. It is also used to produce 6-bromo-2-methoxypyridine.

BRN: 108922

Chemical Properties: White to light yellow crystalline powder

Purification Methods: Purify 2,6-dibromopyridine by steam distillation, then recrystallise it twice from EtOH. It does not form an HgCl2 salt. [den Hertog & Wibaut Recl Trav Chim Pays Bas 51 381 1932, Beilstein 20/5 V 435.]

9. Toltal 232 Suppliers View more

Hebei Yanxi Chemical Co.,Ltd

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Wuhan Fortuna Chemical Co., Ltd.

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Hebei Saisier Technology Co., LTD

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Baoji Guokang Healthchem co.,ltd

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10. Related Questions

: How to apply and prepare 2,6-Dibromopyridine efficiently? 2,6-Dibromopyridine is a traditional organic chemical product. It is insoluble in water and soluble in methanol, ethanol, dioxane, chloroform, etc. It is mainly used in the fields of high-end fine ch..; What is the synthesis method of 2,6-dibromopyridine?2,6-Dibromopyridine is a traditional organic chemical product that is insoluble in water but soluble in methanol, ethanol, dioxane, and chloroform. It is mainly used in the field of high-end fine chem..

11. Realated Product Infomation