-
Copper(II) sulfate
- CAS:7758-98-7
- MW:159.6086
- MF:CuO4S
Copper and its compounds are on the Community Right-To-Know List. Copper Sulphate (CAS NO.7758-98-7) is reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
Hazard Codes of?Copper Sulphate (CAS NO.7758-98-7):?Xn,N,Xi
Risk Statements: 50/53-22-51-36/37/38?
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R22: Harmful if swallowed.?
R51: Toxic to aquatic organisms.?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-60-61-22?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S60:This material and its container must be disposed of as hazardous waste.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S22:Do not breathe dust.
RIDADR: UN 3288 6.1/PG 3
WGK Germany: 2
RTECS: GL8800000
F: 3
HazardClass: 6.1
PackingGroup: III
A human poison by ingestion. An experimental poison by ingestion, subcutaneous, parenteral, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: gastritis, diarrhea, nausea or vomiting, damage to kidney tubules, and hemolysis. Questionable carcinogen with experimental tumorigenic data.
1.Fire Fighting Measures?
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible.?
Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire.?
2.Handling and Storage?
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.?
Storage: Store in a cool, dry place. Store in a tightly closed container. Store under an inert atmosphere.?
?
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
child | TDLo | oral | 150mg/kg (150mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA |
American Journal of Diseases of Children. Vol. 131, Pg. 149, 1977. |
frog | LDLo | intravenous | 25mg/kg (25mg/kg) | ? | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 76, 1955. |
guinea pig | LDLo | intravenous | 2mg/kg (2mg/kg) | ? | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
human | LDLo | oral | 50mg/kg (50mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
JAMA, Journal of the American Medical Association. Vol. 235, Pg. 801, 1976. |
human | TDLo | oral | 11mg/kg (11mg/kg) | GASTROINTESTINAL: GASTRITIS GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Lancet. Vol. 2, Pg. 700, 1960. |
man | LDLo | oral | 857mg/kg (857mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | Archiv fuer Toxikologie. Vol. 17, Pg. 20, 1958. |
mouse | LD50 | intraperitoneal | 7182ug/kg (7.182mg/kg) | ? | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963. |
mouse | LD50 | intravenous | 23300ug/kg (23.3mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
mouse | LD50 | oral | 369mg/kg (369mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
mouse | LDLo | subcutaneous | 500ug/kg (0.5mg/kg) | ? | Tokyo Joshi Ika Daigaku Zasshi. Journal of Tokyo Women's Medical College. Vol. 48, Pg. 313, 1978. |
rabbit | LD50 | intravenous | 10mg/kg (10mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: FOOD INTAKE (ANIMAL) |
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 301, 1949. |
rat | LD50 | intraperitoneal | 20mg/kg (20mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
rat | LD50 | intravenous | 48900ug/kg (48.9mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
rat | LD50 | oral | 300mg/kg (300mg/kg) | ? | "Antifungal Compounds," Siegel, M.R., and H.D. Sisler, eds., 2 vols., New York, Marcel Dekker 1977Vol. 1, Pg. 507, 1977. |
rat | LD50 | subcutaneous | 43mg/kg (43mg/kg) | ? | Proceedings of the European Society of Toxicology. Vol. 16, Pg. 252, 1975. |
rat | LD50 | unreported | 520mg/kg (520mg/kg) | ? | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(6), Pg. 21, 1982. |
women | LDLo | oral | 47320uL/kg (47.32mL/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
Nephron. Vol. 15, Pg. 74, 1975. |
women | TDLo | oral | 2100ug/kg/5W- (2.1mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: OTHER CHANGES |
Toxicologist. Vol. 54, Pg. 73, 2000. |