Antipyretic Analgesics and NSAIDs    
 
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Antipyretic Analgesics and NSAIDs CAS Diretory

Antipyretic Analgesics and NSAIDs

Antipyretic Analgesics means that it can restore the body temperature of febrile patients to normal, but it has no effect on the body temperature of normal people. It also has moderate analgesic effect, but its intensity is not as strong as morphine and its synthetic substitute. 

NSAIDs are a kind of anti-inflammatory drugs without steroidal structure. It is one of the most widely used drugs in the world. It has the effects of anti-inflammation, anti-rheumatism, analgesia, antipyretic, anti-inflammatory and tumor prevention. 

Antipyretic Analgesics Categories

These agents are instrumental in alleviating pain and fever. The categorization comprises salicylic acid, aniline, and pyrazolone derivatives. 

Among these categories, aniline-based medications not only possess anti-rheumatic properties but also hold the capability to effectively address conditions such as rheumatism and rheumatoid arthritis.

Usage of Antipyretic Analgesics and NSAIDs Products

The utilization of antipyretic analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) extends to various medical scenarios, offering relief from pain, reducing inflammation, and managing fever. Here are some instances of their application:

Pain Relief:

Antipyretic analgesics like acetaminophen (paracetamol) and NSAIDs such as ibuprofen are commonly used to alleviate mild to moderate pain. They are suitable for conditions like headaches, muscle aches, and dental pain.

Fever Reduction:

Both antipyretic analgesics and NSAIDs play a pivotal role in reducing fever. They are instrumental in managing febrile conditions such as infections or inflammatory illnesses.

Inflammatory Conditions:

NSAIDs are particularly effective in alleviating inflammation and associated pain in conditions like arthritis (e.g., osteoarthritis, rheumatoid arthritis), tendonitis, and bursitis.

Postoperative Pain:

After surgical procedures, antipyretic analgesics and NSAIDs are often administered to manage postoperative pain and discomfort.

Menstrual Pain:

NSAIDs are commonly used to mitigate menstrual cramps due to their ability to reduce uterine contractions and prostaglandin production.

Sports Injuries:

Both categories of medications are utilized to alleviate pain and inflammation resulting from sports-related injuries, strains, and sprains.

Chronic Pain Management:

NSAIDs, especially when prescribed by a healthcare professional, may be used for managing chronic pain conditions such as lower back pain.

Headache and Migraine Relief:

Antipyretic analgesics and NSAIDs are often chosen to provide relief from headaches and migraines, due to their pain-relieving properties.

Dental Pain:

These medications are employed to manage dental pain, including toothaches and post-dental procedure discomfort.

It is crucial to note that while these medications are widely used and effective, their usage should be under the guidance of a healthcare professional. The appropriate dosage, duration, and potential interactions with other medications or existing medical conditions should be taken into consideration to ensure their safe and effective use.

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250compouds
Metamizole sodium
Metamizole sodium CAS:68-89-3 MF:C13H16N3NaO4S
solid Metamizole sodium is an organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antirheumatic drug, a peripheral ne..
Indometacin
Indometacin CAS:53-86-1 MF:C19H16ClNO4
Indometacin (CAS 53-86-1) is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, reduce inflammation, and lower fever. It is a white to yellow crystalline powder with a molecular formula of C19H16ClNO4 and a molecular weight of 357.79 g/mol. Indometacin is sparingly ..
Antipyrine
Antipyrine CAS:60-80-0 MF:C11H12N2O
Antipyrine is an analgesic and antipyretic agent.Target: OthersAntipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine was one of the fir..
Psoralen
Psoralen CAS:66-97-7 MF:C11H6O3
Psoralen(Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity.IC50 value:Target:in vitro: Psoralen dosages of 1-10 μM exhibited low cytotoxicity toward chondrocytes. However, a dosage of 100 μM suppressed the proliferation of chondrocytes. Different concentrations..
Etodolac
Etodolac CAS:41340-25-4 MF:C17H21NO3
Etodolac is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM)IC50 value: 53.5 nMTarget: COX1; COX2Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibit..
Nabumetone
Nabumetone CAS:42924-53-8 MF:C15H16O2
Nabumetone, with the chemical formula C15H16O2, has the CAS number 42924-53-8. It is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and swelling. Nabumetone appears as a white to off-white crystalline powder with a slight odor. Its basic structure consists ..
Nimesulide
Nimesulide CAS:51803-78-2 MF:C13H12N2O5S
Nimesulide, with the chemical formula C13H12N2O5S, has the CAS number 51803-78-2. It is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic and anti-inflammatory properties. Nimesulide appears as a yellow crystalline powder with a slight characteristic odor. Its bas..
Carprofen
Carprofen CAS:53716-49-7 MF:C15H12ClNO2
Carprofen, with the chemical formula C15H12ClNO2, has the CAS number 53716-49-7. It is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the class of propionic acid derivatives. It appears as a white to off-white crystalline powder with a slight characteristic odor. Its basic structure cons..
Piroxicam
Piroxicam CAS:36322-90-4 MF:C15H13N3O4S
Piroxicam, with the chemical formula C15H13N3O4S, has the CAS number 36322-90-4. It is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the class of oxicams. Piroxicam appears as a yellow crystalline powder with a slight odor. Its basic structure consists of a pyridinylthiazole ring attach..
Paeonol
Paeonol CAS:552-41-0 MF:C9H10O3
Paeonol, with the chemical formula C9H10O3, has the CAS number 552-41-0. It appears as a white to off-white crystalline powder with a sweet, floral odor. Paeonol is a natural phenolic compound found in the roots of Paeonia suffruticosa and other plants. Its basic structure consists of a benzene ring..
Naproxen
Naproxen CAS:22204-53-1 MF:C14H14O3
Naproxen, with the chemical formula C14H14O3, has the CAS number 22204-53-1. It is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the class of propionic acid derivatives. It appears as a white crystalline powder with no distinct odor. Its basic structure consists of a propionic acid moie..
D-(-)-Salicin
D-(-)-Salicin CAS:138-52-3 MF:C13H18O7
D-(-)-Salicin (CAS 138-52-3) is a natural chemical compound that is commonly found in the bark of willow trees. It appears as a white crystalline powder with a molecular formula of C13H18O7. It is soluble in water and has a slightly bitter taste. The physical properties of D-(-)-Salicin include a me..
2,6-Diaminopyridine
2,6-Diaminopyridine CAS:141-86-6 MF:C5H7N3
2,6-Diaminopyridine (CAS 141-86-6) is a white to light yellow crystalline powder. It has a basic structure consisting of a pyridine ring with amino groups attached at positions 2 and 6. This chemical is soluble in water and has a melting point of approximately 103-105 degrees Celsius. It is also kno..
Betamethasone
Betamethasone CAS:378-44-9 MF:C22H29FO5
Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.Target: Glucocorticoid ReceptorBetamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cau..
Leflunomide
Leflunomide CAS:75706-12-6 MF:C12H9F3N2O2
Leflunomide, with the chemical formula C12H9F3N2O2, has the CAS number 75706-12-6. It is a medication belonging to the class of disease-modifying antirheumatic drugs (DMARDs). Leflunomide appears as a white to yellowish powder with a slight odor. Its basic structure consists of a fluorine atom, a ni..
Ganciclovir
Ganciclovir CAS:82410-32-0 MF:C9H13N5O4
Ganciclovir, with the chemical formula C9H13N5O4, has the CAS number 82410-32-0. It is a synthetic nucleoside analogue that is commonly used as an antiviral medication. Ganciclovir appears as a white to off-white crystalline powder with no distinct odor. Its basic structure consists of a guanine bas..
Aceclofenac
Aceclofenac CAS:89796-99-6 MF:C16H13Cl2NO4
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.Target: COXAceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Ac..
5-Pyrimidinylboronic acid
5-Pyrimidinylboronic acid CAS:109299-78-7 MF:C4H5BN2O2
5-Pyrimidinylboronic acid, with the chemical formula C4H5BN2O2, has the CAS number 109299-78-7. It appears as a white to off-white solid with no distinct odor. The basic structure of 5-Pyrimidinylboronic acid consists of a pyrimidine ring attached to a boronic acid group. This compound is soluble in..
Moxifloxacin hydrochloride
Moxifloxacin hydrochloride CAS:186826-86-8 MF:C21H25ClFN3O4
Moxifloxacin hydrochloride is a hydrochloride comprising equimolar amounts of moxifloxacin and hydrogen chloride. It has a role as an antibacterial drug. It contains a moxifloxacinium(1+).|Moxifloxacin is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as we..
1-(2,6-Dichlorophenyl)-2-indolinone
1-(2,6-Dichlorophenyl)-2-indolinone CAS:15307-86-5 MF:C14H11Cl2NO2
Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.
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