CAS 2156-56-1 Sodium dichloroacetate | Products & Prices & Suppliersts

Sodium dichloroacetate is a metabolic regulator in cancer cells' mitochondria with anticancer activity. Sodium dichloroacetate inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. Sodium dichloroacetate increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. Sodium dichloroacetate also works as NKCC inhibitor[1].

Sodium Dichloroacetate is the sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion inhibits pyruvate dehydrogenase kinase, resulting in the inhibition of glycolysis and a decrease in lactate production. This agent may stimulate apoptosis in cancer cells by restoring normal mitochondrial-induced apoptotic signaling.|A derivative of ACETIC ACID that contains two CHLORINE atoms attached to its methyl group.

ldentification

: Cas NO.: 2156-56-1; CID: 517326; Mw: 150.92391; MF: C2HCl2NaO2; Name:Sodium dichloroacetate (Related Reference); Synonyms: Acetic acid, 2,2-dichloro-, sodium salt (1:1); ACETIC ACID,DICHLORO-,SODIUM SALT; Cpc 211; dichloroacetate de sodium; dichloroacetate sodium salt; dichloroacetate,sodiumsalt; dichloroacetic acid sodium salt;; EINECS: 218-461-3

Safety Data

: [Risk Codes] R36/37/38:Irritating to eyes, respiratory system and skin; [Safety Statements] S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S37/39:Wear suitable gloves and eye/face protection; Hazard Symbols: HazardClass: 8

Properties

: Appearance:White Powder; Molecular Weight:150.92391; Density:Relative density (water = 1): 1.56; Boiling Point:194°Cat760mmHg; Melting Point:198℃ (dec.); Flash Point:194°Cat760mmHg; Storage Temperature:Inert atmosphere,2-8°C; Solubility:soluble in cold water; Stability:Stable under normal temperatures and pressures.; More Properties>>

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Question & Answer

: What is Sodium dichloroacetate and how is it used? Sodium dichloroacetate, also known as Sodium dichloroacetate in English, is a white solid powder at room temperature and pressure. It has a certain alkalinity and strong hygroscopicity, good solubili.. Sep 21 2024; What is Sodium dichloroacetate? Sodium Dichloroacetate is the sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion inhibits pyruvate dehydrogenase kinase, resulting in the inhibition of glyc.. Aug 29 2020; Can Sodium Dichloroacetate be a Potential Treatment for Cancer and Vascular Dementia? Sodium Dichloroacetate (DCA) is a promising compound with potential antineoplastic activity. By inhibiting pyruvate dehydrogenase kinase, DCA inhibits glycolysis and reduces lactate production, potent.. Dec 30 2019