1.Identification
1.1 GHS Product identifier
| Product name | diglyme |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | diethyleneglycol dimethylether |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Processing aids, not otherwise listed |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | WWW.GuideChem.COM |
|---|---|
| Address | 8F, Block C, No.3 Building, Zijin Plaza, No.701, Gudun Road, Hangzhou, Zhejiang 310030, China |
| Telephone | +86-571-89739798 |
| Fax | 86(21)54365166 |
1.5 Emergency phone number
| Emergency phone number | +86-571-89739798 |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Flammable liquids, Category 3
Reproductive toxicity, Category 1B
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H226 Flammable liquid and vapour H360FD |
| Precautionary statement(s) | |
| Prevention | P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. |
| Response | P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P308+P313 IF exposed or concerned: Get medical advice/ attention. |
| Storage | P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| diglyme | diglyme | 111-96-6 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower.
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Give one or two glasses of water to drink.
4.2 Most important symptoms/effects, acute and delayed
INGESTION (severe cases): nausea, vomiting, abdominal cramps, weakness progressing to coma. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Absorption, Distribution and Excretion
The major route of elimination is through the urine. Ninety-six hours after oral application of 6.84 mg diglyme/kg body weight to male Sprague-Dawley rats, 90% of the dose was excreted via urine, 3.6% as carbon dioxide, and 2.9% in the feces. Only 1.7% of the dose remained in the carcass.
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Fire Extinguishing Agents: Dry chemical, foam, carbon dioxide (USCG, 1999)
5.2 Specific hazards arising from the chemical
This chemical is combustible.
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
NIOSH recommends reducing exposure to lowest feasible concn & preventing contact with the skin. /Glycol ethers/
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | clear liquid |
|---|---|
| Colour | Colorless liquid |
| Odour | Mild odor |
| Melting point/ freezing point | -68\u00b0C(lit.) |
| Boiling point or initial boiling point and boiling range | 162\u00b0C(lit.) |
| Flammability | Flammable. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 57\u00b0C |
| Auto-ignition temperature | 187.78\u00b0C |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | 1.089 cP at 20\u00b0C |
| Solubility | In water:Miscible |
| Partition coefficient n-octanol/water (log value) | log Kow = -0.36 |
| Vapour pressure | 3 mm Hg ( 20 \u00b0C) |
| Density and/or relative density | 0.944g/mLat 20\u00b0C(lit.) |
| Relative vapour density | 4.6 (vs air) |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
CombustibleA violent explosion occurred when lithium aluminum hydride was being used to dry diethylene glycol dimethyl ether. The ignition may have occurred due to the presence of large amounts of water or perhaps peroxide formed in the ether. About 75% of the ether had been removed when the explosion occurred, [MCA Case History 1494 (1968)].
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
11.Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 2978 mg/kg bw
- Inhalation: LC50 Rat inhalation >11 mg/L/7 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Diethylene glycol dimethyl ether had a 37.0% COD removal at 30\u00b0C from a starting concentration of 600 mg COD/L (time period not given) indicating little degradation compared to 95% degradation of ethylene glycol monophenyl ether(1). Diethylene glycol dimethyl ether was degraded 33% after 25 days and a 7 day lag period using an activated sludge from an industry producing the chemical(2). 40% was removed in a 1% salt solution after 25 days with a 20 day lag period, higher salt concentrations inhibited the degradation of diethylene glycol dimethyl ether(2).
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for diethylene glycol dimethyl ether(SRC), using a log Kow of -0.36(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of diethylene glycol dimethyl ether is estimated as 15(SRC), using a log Kow of -0.36(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that diethylene glycol dimethyl ether is expected to have very high mobility in soil.
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN3271 | IMDG: UN3271 | IATA: UN3271 |
14.2 UN Proper Shipping Name
| ADR/RID: ETHERS, N.O.S. |
| IMDG: ETHERS, N.O.S. |
| IATA: ETHERS, N.O.S. |
14.3 Transport hazard class(es)
| ADR/RID: 3 | IMDG: 3 | IATA: 3 |
14.4 Packing group, if applicable
| ADR/RID: III | IMDG: III | IATA: III |
14.5 Environmental hazards
| ADR/RID: no | IMDG: no | IATA: no |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| diglyme | diglyme | 111-96-6 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 10, 2017 |
|---|---|
| Revision Date | Aug 10, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/