Antineoplastic Agents    
 
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Antineoplastic Agents CAS Diretory

Antineoplastic Agents

Antineoplastic agents, often referred to as anticancer drugs or chemotherapy drugs, are a class of medications designed to treat and manage cancer. These agents work by targeting and interfering with the processes that allow cancer cells to grow, divide, and spread. Unlike normal cells, cancer cells tend to proliferate rapidly and uncontrollably. Antineoplastic agents are developed to specifically target and disrupt these abnormal growth patterns, with the goal of reducing or eliminating cancerous tumors.

Antineoplastic Agents categories

According to the effect of the drug, it can be divided into cytotoxic drugs and non-cytotoxic drugs. When traditional cytotoxic drugs kill cancer cells, they will also cause different damage to normal tissues and cells.

Pharmaceutical technology has advanced, leading to the evolution of antineoplastic drugs. These drugs have transitioned from non-selective and single cytotoxic drugs to more targeted and less harmful options. This advancement has ushered in a new era in the research and development of antineoplastic drugs. This has led to a new era in the research and development of antineoplastic drugs. 

Usage of Antineoplastic Agents products

Antineoplastic Agents play a pivotal role in the realm of medical treatment. These agents are made to fight and stop the growth of cancer cells by targeting the complex mechanisms involved. Doctors use anticancer drugs in various cancer treatments, such as chemotherapy, targeted therapy, and immunotherapy, which makes them important in modern cancer care. 

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2000compouds
Oxaliplatin
Oxaliplatin CAS:61825-94-3 MF:C8H12N2O4Pt
Oxaliplatin, with the chemical formula C8H14N2O4Pt, has the CAS number 61825-94-3. It is a platinum-based antineoplastic agent used in cancer chemotherapy. Oxaliplatin appears as a yellow powder with no distinct odor. Its basic structure consists of a platinum atom coordinated to two amine groups an..
5-Fluorouracil
5-Fluorouracil CAS:51-21-8 MF:C4H3FN2O2
5-Fluorouracil (CAS 51-21-8) is a white crystalline powder that is commonly used in the field of oncology. Its basic structure consists of a fluorine atom attached to a uracil ring, which is a pyrimidine base. This compound is sparingly soluble in water, but it can dissolve in organic solvents such ..
Methotrexate
Methotrexate CAS:59-05-2 MF:C20H22N8O5
Methotrexate (CAS 59-05-2) is a yellow, crystalline powder that is commonly used as a chemotherapy drug. It has a basic structure consisting of a pteridine ring fused to a p-aminobenzoic acid moiety. Methotrexate is sparingly soluble in water, but it dissolves well in organic solvents such as methan..
Carboplatin
Carboplatin CAS:41575-94-4 MF:C6H12N2O4Pt
Carboplatin, with the chemical formula C6H12N2O4Pt, has the CAS number 41575-94-4. It is a platinum-containing antineoplastic agent used in cancer chemotherapy. It appears as a white crystalline powder with no distinct odor. Its basic structure consists of a platinum atom attached to a carboplatin m..
Tamoxifen citrate
Tamoxifen citrate CAS:54965-24-1 MF:C32H37NO8
Tamoxifen citrate is a chemical compound with the CAS number 54965-24-1. It is a selective estrogen receptor modulator (SERM) that is commonly used in the treatment of breast cancer. Tamoxifen citrate appears as a white to off-white crystalline powder. It has no distinct odor. The molecular formula ..
Doxorubicin hydrochloride
Doxorubicin hydrochloride CAS:25316-40-9 MF:C27H30ClNO11
Doxorubicin hydrochloride is a cytotoxic anthracycline antibiotic for the treatment of multiple cancers. The possible mechanisms by which doxorubicin acts in the cancer cell are intercalation into DNA and disruption of topoisomerase-II-mediated DNA repair.
Ellagic acid
Ellagic acid CAS:476-66-4 MF:C14H6O8
Ellagic acid, with the chemical formula C14H6O8, has the CAS number 476-66-4. It appears as a yellowish-white powder with no distinct odor. The basic structure of ellagic acid consists of a fused four-ring structure with hydroxyl groups attached to it. This compound is sparingly soluble in water, bu..
Resveratrol
Resveratrol CAS:501-36-0 MF:C14H12O3
Resveratrol, with the chemical formula C14H12O3 and CAS number 501-36-0, is a natural polyphenol found in various plants, particularly in red grapes and berries. It is well-known for its potential health benefits. Resveratrol appears as a white to off-white powder with no distinct odor. Its molecula..
Cytarabine
Cytarabine CAS:147-94-4 MF:C9H13N3O5
Cytarabine (CAS 147-94-4) is a white crystalline powder that is commonly used in the treatment of various types of cancer. Its basic structure consists of a cytosine base attached to an arabinose sugar molecule. This chemical is sparingly soluble in water, but it can be dissolved in dimethyl sulfoxi..
Temozolomide
Temozolomide CAS:85622-93-1 MF:C6H6N6O2
Temozolomide (NSC 362856; CCRG 81045) is an oral DNA alkylating agent used to treat some brain cancers. Solid Temozolomide is an imidazotetrazine that is 3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine which is substituted at positions 3, 4, and 8 by methyl, oxo, and carboxamide groups, respectively. A ..
Bicalutamide
Bicalutamide CAS:90357-06-5 MF:C18H14F4N2O4S
Bicalutamide, with the chemical formula C18H14F4N2O4S, has the CAS number 90357-06-5. It is a non-steroidal antiandrogen drug used primarily in the treatment of prostate cancer. Bicalutamide appears as a white to off-white crystalline powder. It has no distinct odor. The basic structure of bicalutam..
Exemestane
Exemestane CAS:107868-30-4 MF:C20H24O2
white to light yellow crystal powderChEBI: A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breat..
Letrozole
Letrozole CAS:112809-51-5 MF:C17H11N5
white to light yellow crystalLetrozole (trade name: Femara) is an orally active nonsteroidal aromatase inhibitor. As a competitive inhibitor of the aromatase, Letrozole inhibits the conversion of androgens to estrogen (estrogen stimulates breast tissues and breast cancer reoccurrence) and gonadal st..
Docetaxel
Docetaxel CAS:114977-28-5 MF:C43H53NO14
Docetaxel, with the chemical formula C43H53NO14, has the CAS number 114977-28-5. It is a chemotherapy drug belonging to the class of taxanes. It appears as a white to almost white powder. Docetaxel has no distinct odor. Its basic structure consists of a complex arrangement of carbon, hydrogen, nitro..
Gemcitabine hydrochloride
Gemcitabine hydrochloride CAS:122111-03-9 MF:C9H12ClF2N3O4
Suitable for the treatment of inoperable advanced or metastatic pancreatic cancer and the treatment of locally advanced or metastatic non-small cell lung cancer, the treatment of intermediate and advanced non-small cell lung cancer, non-small cell lung cancer, pancreatic cancer, bladder cancer, brea..
Bortezomib
Bortezomib CAS:179324-69-7 MF:C19H25BN4O4
Yellow SolidChEBI: L-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at Nalpha by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid tha reversibly inhibits the 26S proteasome.Bortezomib, a modified dipeptidyl boronic acid, is a therap..
Gefitinib
Gefitinib CAS:184475-35-2 MF:C22H24ClFN4O3
Light-Yellow Crystalline PowderGefitinib was introduced in Japan as a daily oral monotherapy for the treatment of inoperable or recurrent non-small cell lung cancers (NSCLC). This anilinoquinazoline derivative can be synthesized in 6 steps starting from 6,7-dimethoxyquinazolin-4(3H)-one by successiv..
Lenalidomide
Lenalidomide CAS:191732-72-6 MF:C13H13N3O3
Yellow SolidChEBI: A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha.Lenalidomide is a derivative of thalidomide differing in the presence of anamino moiety in the 4-posi..
Sorafenib tosylate
Sorafenib tosylate CAS:284461-73-0 MF:C21H16ClF3N4O3
Sorafenib tosylate is the tosylate form of sorafenib, which is a drug approved for the treatment of hepatocellular carcinoma and the treatment of advanced renal cell carcinoma (primary kidney cancer). Hepatocellular carcinoma accounts for the vast majority of primary liver cancers (85–90%). [1] App..
Capecitabine
Capecitabine CAS:154361-50-9 MF:C15H22FN3O6
Colourless solidCapecitabine is a new oral fluoropyrimidine carbamate for patients withadvanced neoplastic disease, approved as Xeloda for the treatment of refractorymetastatic breast cancer after failure on Paclitaxel and an anthracycline-basedchemotherapy regimen ; it is a prodrug of doxifluridine..
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