Encyclopedia   /  Others  /  Paraffin  /  Pharmaceutical Intermediates
Paraffin wax structure

Paraffin wax

Propafenone, with the chemical formula C21H27NO3 and CAS registry number 8002-74-2, is a compound known for its applications in the treatment of cardiac arrhythmias. This white crystalline powder, also referred to as Rhythmol, is characterized by its antiarrhythmic properties. It works by blocking certain electrical signals in the heart, helping to restore a normal heart rhythm. Propafenone is commonly used in the management of atrial fibrillation and ventricular arrhythmias. It is available in various formulations, including tablets and extended-release capsules. As with any medication, it is important to follow the prescribed dosage and consult a healthcare professional for personalized advice. Propafenone may cause side effects such as dizziness, nausea, and changes in heart rate. It is contraindicated in individuals with certain heart conditions and should be used with caution in patients with liver or kidney impairment. Overall, Propafenone plays a crucial role in the management of cardiac arrhythmias, helping to improve the quality of life for individuals with these conditions.
View more+
 
1. Names and Identifiers
1.1 Name
Paraffin wax
1.2 Synonyms
PARAFFIN IN BLOCK FORM 42-44 1 KG; PARAFFIN IN BLOCK FORM 42-44 25 KG; PARAFFIN IN BLOCK FORM 46-48 1 KG; PARAFFIN IN BLOCK FORM 46-48 25 KG; PARAFFIN IN PASTILLE FORM 51-53 PH EUR,B; PARAFFIN IN PASTILLE FORM 52-54 PH EUR,B; PARAFFIN IN PASTILLE FORM 56-58 PH EUR,B; PARAFFIN IN PASTILLE FORM 57-60 PH EUR,B;
1.3 CAS No.
8002-74-2
1.5 EINECS
232-315-6
1.6 Molecular Formula
C21H27NO3
1.7 Inchi
InChI=1/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3
1.8 InChkey
JWHAUXFOSRPERK-UHFFFAOYNA-N
1.9 Canonical Smiles
CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1
2. Properties
2.1 Appearance
WHITE POWDER
2.2 StorageTemp
Store below +30°C.
3. Use and Manufacturing
3.1 Description

Propafenone, with the chemical formula C21H27NO3, has the CAS number 8002-74-2. It is a white to off-white powder with a faint odor. Its basic structure consists of a phenyl ring attached to a propylamine chain. This compound is slightly soluble in water. Propafenone may cause irritation to the skin and eyes. It is also harmful if swallowed or inhaled. The primary hazard is the potential for cardiovascular effects. Immediate medical attention should be sought in case of ingestion or exposure. Propafenone is commonly used as an antiarrhythmic medication to treat irregular heart rhythms.

Applicable Fields

Cardiology: Propafenone is primarily used in the field of cardiology as an antiarrhythmic medication. Its purpose is to restore and maintain normal heart rhythm in patients with certain types of irregular heartbeats. The mechanism of action involves blocking certain ion channels in the heart, which helps to regulate the electrical signals and prevent abnormal rhythms.

Storage

Conditions: Store in a cool and dry place, away from direct sunlight.

4. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word.

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

5.Other Information
Description
Paraffin wax is mostly found as a white, odorless, tasteless, waxy solid, with a typical melting point between about 46 and 68°C (115 and 154°F) and a density of approximately 900, is insoluble in water, but soluble in ether, benzene, and certain esters. Paraffin wax is often classed as a stable chemical since it is unaffected by most common chemical reagents but burns readily.
Paraffin wax is the common name for the mixture of solid higher alkanes, the molecular formula is CnH2n+2, where n=20-40. The excess oil residue in the wax is removed through the process of petroleum refining. It is then deoiled and separated by vacuum distillation. The main component of refined paraffin is saturated normal alkanes with carbon number of about 20-40, containing a small amount of isomers and alkanes.
Physical properties
Paraffin wax, also known as crystalline wax, is usually a white, odorless waxy solid. It melts at 47°C-64°C and has a density of about 0.9g/cm3. It is soluble in gasoline, carbon disulfide, xylene, ether, benzene, chloroform, and tetrachloride. Non-polar solvents such as carbon, naphtha, etc., are insoluble in polar solvents such as water and methanol. Pure paraffin is a good insulator, its resistivity is 1013-1017 ohm·m, which is higher than most materials except some plastics (especially Teflon).
Paraffin wax
Fully refined paraffin waxes are a hard, white crystalline material derived from petroleum. Paraffin waxes are predominately composed of normal, straight-chain hydrocarbons. The water-repellent and thermoplastic properties of paraffin waxes make them ideal for many applications. Typical end uses include cereal, delicatessen, and household wrap, corrugated containers, candles, cheese and vegetable coatings, and hot melt adhesives.
Composition
Paraffin wax is a mixture of solid higher alkanes, the molecular formula of the main component is CnH2n+2, where n=17~35. The main components are straight-chain alkanes, a small amount of alkane with individual branches and monocyclic cycloalkanes with long side chains; straight-chain alkanes are mainly n-docosane (C22H46) and n-octadecane (C28H58) . 
Wax
Wax is of two general types: (i) paraffin wax in petroleum distillates and (ii) microcrystalline wax in petroleum residua.
Paraffin wax is a solid crystalline mixture of straightchain (normal) hydrocarbons ranging from 20 to 30 carbon atoms per molecule, and even higher.
Paraffin wax is a solid crystalline mixture of straightchain (normal) hydrocarbons ranging from C20 to C30 and possibly higher, that is, CH3(CH2)nCH3 , where n≥18. It is distinguished by its solid state at ordinary temperatures (25°C, 77°F) and low viscosity (35–45 SUS at 99°C, 210°F) when melted. However, in contrast to petroleum wax, petrolatum (petroleum jelly), although solid at ordinary temperatures, does in fact contain both solid and liquid hydrocarbons. It is essentially a low-melting, ductile, microcrystalline wax.
Microcrystalline waxes form approximately 1–2% w/w of crude oil and are valuable products having numerous applications. These waxes are usually obtained from heavy lube distillates by solvent dewaxing and from tank bottom sludge by acid clay treatment. However, these crude wax products usually contain appreciable quantity (10–20% w/w) of residual oil and, as such, are not suitable for many applications such as paper coating, electrical insulation, textile printing, and polishes.
Microcrystalline waxes
Microcrystalline waxes are a type of wax produced by de-oiling petrolatum, as part of the petroleum refining process. In contrast to the more familiar paraffin wax, which contains mostly unbranched alkanes, microcrystalline wax contains a higher percentage of iso-paraffin (branched) and naphthene hydrocarbons. It is characterized by the fineness of its crystals in contrast to the larger crystal of paraffin wax. It consists of high-molecular-weight saturated aliphatic hydrocarbons. It is generally darker, more viscous, denser, tackier, and more elastic than paraffin waxes, and has a higher molecular weight and melting point. The elastic and adhesive characteristics of microcrystalline waxes are related to the non-straightchain components that they contain. Typical microcrystalline wax crystal structure is small and thin, making them more flexible than paraffin wax.
Microcrystalline waxes
Microcrystalline waxes when produced by wax refiners are typically produced to meet a number of ASTM specifications, which include congealing point (ASTM D938), needle penetration (D1321), color (ASTM D6045), and viscosity (ASTM D445). Microcrystalline wax is also a key component in the manufacture of petrolatum. The branched structure of the carbon chain backbone allows oil molecules to be incorporated into the crystal lattice structure. The desired properties of the petrolatum can be modified by using microcrystalline wax bases of different congeal points (ASTM D938) and needle penetration (ASTM D1321).
Uses
Used in the production of candles, crayons, wax paper, rubber, wires, cables, plates, waterproof materials, electrical insulation, food packaging, precision casting, general telecommunications equipment, textiles, printing, metal rust prevention, and other chemicals required by various industrial sectors raw material.Paraffin wax can also be used for oxidation to generate synthetic fatty acids. Paraffin wax can also be made into detergents, emulsifiers, dispersants, plasticizers, greases, etc.As a kind of latent heat storage material, paraffin wax has the advantages of large latent heat of phase change, small volume change during solid-liquid phase change, good thermal stability, no supercooling phenomenon, and low price. It is used in aviation, aerospace, microelectronics, etc. Various fields such as scientific and technological systems and house energy saving have been widely used.
Occurrence
Paraffin wax is a hydrocarbon mixture extracted from certain distillates of petroleum, shale oil or other bituminous mineral oils. The main component is solid alkanes, which is odorless and tasteless, and is a white or light yellow translucent solid. Paraffin wax has many uses, mainly used in the manufacture of matches, fiberboard, tarpaulin and so on.
Application
1. Paraffin wax can be made into flake or needle crystals obtained by solvent dewaxing or freezing crystallization of wax, pressing dewaxing to obtain wax paste, and then solvent deoiling and refining. Used to make higher fatty acids, higher alcohols, matches, candles, waterproofing agents, ointments, electrical insulating materials, etc.2. Paraffin wax is divided into food grade (food grade and packaging grade, the former is excellent) and industrial grade. Food grade is non-toxic and industrial grade is not edible.3. Because of its high oil content, crude paraffin is mainly used to make matches, fiberboards, tarpaulins, etc. After adding polyolefin additives to paraffin wax, its melting point increases, adhesion and flexibility increase, and it is widely used in moisture-proof and waterproof packaging paper, cardboard, surface coating of certain textiles and candle production.4. After immersing the paper in paraffin wax, various wax papers with good waterproof performance can be prepared, which can be used in food, medicine and other packaging, metal rust prevention and printing industries; after paraffin wax is added to cotton yarn, the textiles can be soft, smooth and smooth. It is elastic; paraffin wax can also be used to make detergents, emulsifiers, dispersants, plasticizers, greases, etc.5. Fully refined paraffin and semi-refined paraffin have a wide range of uses. They are mainly used as components and packaging materials for food, oral medicines and certain commodities (such as wax paper, crayons, candles, carbon paper), coating materials for baking containers, and Fruit preservation, insulation of electrical components, improvement of rubber aging resistance and flexibility, etc.
Description
Paraffin wax, also commonly called ‘paraffin’, is a colourless or white, tasteless, odourless, translucent waxy solid. Paraffin wax has a typical melting point between about 46°C and 68°C. Pure paraffin wax is a combustible substance and insoluble in water but soluble in petroleum solvents and stable under normal conditions of use. Paraffin has been identified as an excellent electrical insulator. It is also used in the manufacturing of paraffin papers, candles, food packaging materials, varnishes, floor polishes, to extract perfumes from flowers, in lubricants, and cosmetics. It is also used in water-proofing wood, and cork.
Chemical Properties
Paraffin wax is colorless or white with an odorless mass. It consists of a mixture of solid aliphatic hydrocarbons. Paraffin is used in the manufacture of paraffin papers, candles, food packaging materials, varnishes, floor polishes, to extract perfumes from flowers, in lubricants, and cosmetics. It is also used in waterproofing wood and cork.
Uses
Paraffin wax, or hard wax, is a mixture of solid hydrocarbons, mainly alkanes. Paraffinwaxcan beadded to medicinal agents. Petroleumwax and petrolatum are the only hydrocarbons permitted for use in food products. Paraffin wax is used as a household wax and extensively as a coating for food containers and wrappers.
Uses
Paraffin Wax is used to embed tissues to be used in research.
Uses
Paraffin wax can be used as a phase changing material in a wide range of applications which include solar based water heaters, microcapsules and thermal energy devices (TEDs).
Production Methods
Paraffin is manufactured by the distillation of crude petroleum or shale oil, followed by purification by acid treatment and filtration. Paraffins with different properties may be produced by controlling the distillation and subsequent congealing conditions.
Synthetic paraffin, synthesized from carbon monoxide and hydrogen is also available;
Definition
A solid mixture of hydrocarbons, obtained from petroleum.
General Description
White translucent tasteless odorless solids. Density 0.88- 0.92 g / cm3. Insoluble in water. Melting range 47-65°C. Used in candles, lubricants, crayons, floor polishes, cosmetics, chewing gum.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Paraffin wax, may be incompatible with strong oxidizing agents. Charring may occur followed by ignition of unreacted portion and other nearby combustibles. In other settings, mostly unreactive. Not affected by aqueous solutions of acids, alkalis, most oxidizing agents, and most reducing agents. When heated sufficiently or when ignited in the presence of air, oxygen or strong oxidizing agents, they burn exothermically.
Health Hazard
Exposures to paraffi n for a prolonged period cause several types of skin disorders, The adverse health effects to skin include chronic dermatitis, wax boils, folliculitis, comedones, papules, melanoderma, and hyperkeratoses. Studies of Hendricks et al. indicated the development of carcinoma of the scrotum in workers exposed to crude petroleum wax. Carcinoma of the scrotum in occupational workers began with a normal hyperkeratotic nevus-like lesion, which subsequently resulted in a squamous cell carcinoma.
Flammability and Explosibility
Notclassified
Pharmaceutical Applications
Paraffin is mainly used in topical pharmaceutical formulations as a component of creams and ointments. In ointments, it may be used to increase the melting point of a formulation or to add stiffness. Paraffin is additionally used as a coating agent for capsules and tablets, and is used in some food applications. Paraffin coatings can also be used to affect the release of drug from ion-exchange resin beads.
Safety Profile
A skin and eye irritant. Questionable carcinogen with experimental tumorigenic data by implant route. Many paraffin waxes contain carcinogens. Fumes cause lung damage. See also PARAFFIN HYDROCARBONS.
Safety
Paraffin is generally regarded as an essentially nontoxic and nonirritant material when used in topical ointments and as a coating agent for tablets and capsules. However, granulomatous reactions (paraffinomas) may occur following injection of paraffin into tissue for cosmetic purposes or to relieve pain. Long-term inhalation of aerosolized paraffin may lead to interstitial pulmonary disease. Ingestion of a substantial amount of white soft paraffin has led to intestinal obstruction in one instance.
Synthesis
Synthesized by the Fischer–Tropsch process from carbon monoxide and hydrogen, which are catalytically converted to a mixture of paraffin hydrocarbons. The lower molecular weight fractions are removed by distillation and the residue is hydrogenated and further treated by percolation through activated charcoal.
storage
Paraffin is stable, although repeated melting and congealing may alter its physical properties. Paraffin should be stored at a temperature not exceeding 40°C in a well-closed container.
Regulatory Status
Accepted in the UK for use in certain food applications. Included in the FDA Inactive Ingredients Database (oral capsules and tablets, topical emulsions, and ointments). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
6. Toltal 688 Suppliers View more
Tel: Update Time:2024/11/15
Tel: Update Time:2024/11/15
Tel: Update Time:2024/11/14
Tel: Update Time:2024/11/15
Tel: Update Time:2024/11/15
7. Related Questions
What are the distinctions between kerosene and paraffin wax? Coalffin wax is often confused, but they have certain differences in chemical composition and use. Exploring the differences between the two helps to understand their respective application areas and..
What is the connection between Paraffin Wax and mineral oil? Paraffin WAX and mineral oil are derived from oil products. Understanding the relationship between Paraffin Wax and mineral oil can help better understand their applications in industry and daily lif..
What are the distinctions between Paraffin Wax and Beeswax? Although Paraffin Wax and beeswax are similar in appearance, they have significant differences in sources, composition and use. Understanding the differences between the two can help us better choose..
Which wax is better for candle making: Soy wax or Paraffin wax? When making candles, it is important to choose the right wax material. Soy wax and Paraffin WAX each have their own unique features. Understanding the advantages and disadvantages of these two will h..
8. Realated Product Infomation
 
 
 
Cancel
 
Popular Searches
Request For Quotation