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(R)-3-Piperidinamine dihydrochloride

CAS：334618-23-4
MW:173.081
MF：C5H14Cl2N2

(R)-3-Piperidinamine dihydrochloride, with the chemical formula C5H16Cl2N2 and CAS registry number 334618-23-4, is a compound known for its pharmaceutical applications. This white crystalline powder is characterized by its piperidine and amine functional groups. It is commonly used as a chiral building block in the synthesis of various drugs, including antiviral and antipsychotic agents. (R)-3-Piperidinamine dihydrochloride exhibits high selectivity and potency in biological systems, making it a valuable tool in medicinal chemistry. Its stereochemistry plays a crucial role in its biological activity, as it interacts with specific receptors and enzymes. This compound has been extensively studied for its pharmacological properties and therapeutic potential. Further research is being conducted to explore its applications in drug discovery and development.

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Names and ldentifier
Properties
Use and Manufacturing
Safety and Handling
Msds
Other Information
Computational chemical data
Related Questions
Realated Product Infomation

1. Names and Identifiers

1.1 Name: (R)-3-Piperidinamine dihydrochloride

1.2 Synonyms: (3R)-3-Piperidinamine dihydrochloride; (3R)-Piperidin-3-amindihydrochlorid; (3R)-Piperidin-3-amine dihydrochloride; (R)-(-)-3-AMINOPIPERIDINE DIHYDROCHLORIDE; (R)-(-)-3-Piperidinamine dihydrochloride; (R)-3-Aminopiperidine 2hcl; (R)-3-AMINOPIPERIDINE DIHYDROCHLORIDE; (R)-3-piperidinamine di-HCl; (R)-3-Piperidinaminedihydrochloride; (R)-Piperidin-3-amine dihydrochloride; (R)-PIPERIDIN-3-YLAMINE DIHYDROCHLORIDE; (R)-PIPERIDINE-3-AMINE DIHYDROCHLORIDE; 3-Piperidinamine, (3R)-, hydrochloride (1:2); Linagliptin interMediate D; MFCD06799458; R-3-AMINOPIPERIDINE DIHCL; R-3-AMnio piperidine dihydrochloride;

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1.3 CAS No.: 334618-23-4

1.4 CID: 16211333

1.5 EINECS: 608-870-9

1.6 Molecular Formula: C5H14Cl2N2

1.7 Inchi: InChI=1S/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H/t5-;;/m1../s1

1.8 InChkey: GGPNYXIOFZLNKW-ZJIMSODOSA-N

1.9 Canonical Smiles: C1CC(CNC1)N.Cl.Cl

1.10 Isomers Smiles: C1C[C@H](CNC1)N.Cl.Cl

2. Properties

2.1 Appearance: White to tan Powder

2.2 Chemical Properties: White powder (R)-3-Piperidinamine dihydrochlorideSupplier

2.3 Color/Form: Powder

2.4 Water Solubility: soluble in water

2.5 StorageTemp: Inert atmosphere,Room Temperature

3. Use and Manufacturing

3.1 Description

(R)-3-Piperidinamine dihydrochloride, with the chemical formula C5H16Cl2N2, has the CAS number 334618-23-4. It appears as a white to off-white crystalline powder. This compound does not have a distinct odor. The basic structure of (R)-3-Piperidinamine dihydrochloride consists of a piperidine ring with an amino group attached to one of the carbon atoms. (R)-3-Piperidinamine dihydrochloride is soluble in water. Safety information regarding this compound is not available.

Applicable Fields

There is no information available regarding the applicable fields and purpose of (R)-3-Piperidinamine dihydrochloride or its mechanism of action.

Storage

ConditionsStore in a cool and dry place.

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4. Safety and Handling

4.1 Safety: Safety Information of (R)-3-Aminopiperidine dihydrochloride (334618-23-4):
Hazard Codes: Xn
Risk Statements: 22-37/38-41
22: Harmful if swallowed
37/38: Irritating to respiratory system and skin
41: Risk of serious damage to eyes
Safety Statements: 26-39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
39: Wear eye/face protection
WGK Germany: 2
F: 10-21

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4.2 Sensitive: Hygroscopic

4.3 Specification: ?(R)-3-Aminopiperidine dihydrochloride (334618-23-4) is also known as?(R)-Piperidin-3-ylamine
dihydrochloride ; (R)-Piperidine-3-amine dihydrochloride ; (R)-(-)-3-Aminopiperidine dihydrochloride ; (R)-3-Piperidinamine dihydrochloride ; R-3-Aminopiperidine dihcl ; (R)-(-)-3-Aminopiperidine 2hcl ; (R)-3-Aminopiperidine 2hcl .?According to the structre, it belongs to?categorie of piperidines, often used in pharmaceticals.

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5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Skin irritation, Category 2

Serious eye damage, Category 1

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H335 May cause respiratory irritation
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/\u2026 P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

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6. Computed Properties

Molecular Weight：173.081g/mol
Molecular Formula：C₅H₁₄Cl₂N₂
Compound Is Canonicalized：True
XLogP3-AA：172.0534038
Monoisotopic Mass：172.0534038
Complexity：54
Rotatable Bond Count：0
Hydrogen Bond Donor Count：4
Hydrogen Bond Acceptor Count：2
Topological Polar Surface Area：38
Heavy Atom Count：：9
Defined Atom Stereocenter Count：1
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：3
CACTVS Substructure Key Fingerprint：AAADccBjAAAGAAAAAAAAAAAAAAAAAAAAAAAsAAAAAAAAAAAAAAAAHAAQAAAACCjBAAQAAALAAAAAAAAAAAAAAAAAAAAAAIAIAAAAQAIAgAAUAAAAEACAAAAQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

7.Other Information

Chemical Properties: White powder

8. Toltal 306 Suppliers View more

CANGZHOU ENKE PHARMA-TECH CO.,LTD

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9. Related Questions

: What is the significance of (R)-3-Piperidinamine dihydrochloride as a chemical and pharmaceutical drug synthesis intermediate?[Overview] (R)-3-Aminopiperidine dihydrochloride, as a chiral compound, is an important chemical and pharmaceutical drug synthesis intermediate. It has important applications in the chemical industry ..

10. Realated Product Infomation