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TRANS-3-HYDROXY-L-PROLINE

CAS：4298-08-2
MW:131.131
MF：C5H9NO3

TRANS-3-HYDROXY-L-PROLINE, with the chemical formula C5H9NO3 and CAS registry number 4298-08-2, is a compound known for its role as a non-proteinogenic amino acid. This compound is a derivative of proline and is characterized by the presence of a hydroxyl group attached to the third carbon atom. TRANS-3-HYDROXY-L-PROLINE is commonly found in collagen, a major component of connective tissues in animals. It plays a crucial role in stabilizing the collagen structure and is involved in various biological processes, including wound healing and tissue repair. Additionally, TRANS-3-HYDROXY-L-PROLINE has been studied for its potential therapeutic applications, such as its anti-inflammatory and antioxidant properties. Further research is being conducted to explore its potential in drug development and medical treatments.

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Names and ldentifier
Properties
Use and Manufacturing
Msds
NMR Spectrum
Other Information
Computational chemical data
Realated Product Infomation

1. Names and Identifiers

1.1 Name: TRANS-3-HYDROXY-L-PROLINE

1.2 Synonyms: (2S,3S)-(-)-3-Hydroxy-L-proline; (2S,3S)-3-Hydroxyproline; (2S,3S)-3-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID; (3S)-3-Hydroxy-L-proline; H-3-HYP-OH; H-HYP(3)-OH; H-PRO(3-HYDROXY)-OH; L-3-HYDROXYPROLINE; L-3-TRANS-HYDROXYPROLINE; L-Proline, 3-hydroxy-, (3S)-; L-Proline, 3-hydroxy-, trans-; Proline, 3-hydroxy-, L-trans-; trans-3-Hydroxy-prolin; trans-3-Hydroxyproline;

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1.3 CAS No.: 4298-08-2

1.4 CID: 440575

1.5 Molecular Formula: C5H9NO3

1.6 Inchi: InChI=1S/C5H9NO3/c7-3-1-2-6-4(3)5(8)9/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1

1.7 InChkey: BJBUEDPLEOHJGE-IMJSIDKUSA-N

1.8 Canonical Smiles: C1CNC(C1O)C(=O)O

1.9 Isomers Smiles: C1CN[C@@H]([C@H]1O)C(=O)O

2. Properties

2.1 Appearance: White to light beige powder

2.2 Chemical Properties: White to light beige powder TRANS-3-HYDROXY-L-PROLINESupplier

2.3 Physical: Solid

2.4 pKa: 2.03±0.40(Predicted)

3. Use and Manufacturing

3.1 Description

TRANS-3-HYDROXY-L-PROLINE, with the chemical formula C5H9NO3, has the CAS number 4298-08-2. It is a derivative of the amino acid proline. TRANS-3-HYDROXY-L-PROLINE appears as a white crystalline powder with no distinct odor. Its basic structure consists of a proline molecule with a hydroxyl group attached to the third carbon atom. This compound is soluble in water. TRANS-3-HYDROXY-L-PROLINE is considered to be safe for use in various applications. However, as with any chemical, proper handling and precautions should be taken to avoid any potential risks.

Applicable Fields

Cosmetics: TRANS-3-HYDROXY-L-PROLINE is commonly used in cosmetic products for its moisturizing and anti-aging properties. It helps to improve the skin's elasticity and firmness, reducing the appearance of wrinkles and fine lines. The mechanism of action in cosmetics involves its ability to promote collagen synthesis and retain moisture in the skin.

Dietary Supplements: This compound is also used in dietary supplements for its potential health benefits. TRANS-3-HYDROXY-L-PROLINE is believed to support joint health and improve the body's natural collagen production. It may help to reduce joint pain and inflammation. The mechanism of action in dietary supplements involves its role in collagen formation and maintenance.

Storage

Conditions: Store in a cool and dry place.

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4. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

no data available

2.2 GHS label elements, including precautionary statements

Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Precautionary statement(s)
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

2.3 Other hazards which do not result in classification

no data available

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5. NMR Spectrum

13C NMR : Predict

1H NMR : Predict

Predict 1H proton NMR

6. Synthesis Route

4298-08-2Total: 14 Synthesis Route

147-85-3 620 Suppliers

4298-08-2 33 Suppliers

312583-31-6

4298-08-2 33 Suppliers

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7. Precursor and Product

precursor:

147-85-3

213131-29-4

120789-99-3

156045-80-6

154631-82-0

213131-33-0

156045-82-8

312583-31-6

156045-81-7

156129-73-6

product:

184046-78-4

187039-57-2

186132-96-7

496841-07-7

412279-18-6

296774-32-8

261350-70-3

8. Computed Properties

Molecular Weight：131.131g/mol
Molecular Formula：C₅H₉NO₃
Compound Is Canonicalized：True
XLogP3-AA：131.058243149
Monoisotopic Mass：131.058243149
Complexity：125
Rotatable Bond Count：1
Hydrogen Bond Donor Count：3
Hydrogen Bond Acceptor Count：4
Topological Polar Surface Area：69.6
Heavy Atom Count：：9
Defined Atom Stereocenter Count：2
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：1
CACTVS Substructure Key Fingerprint：AAADccBiMAAAAAAAAAAAAAAAAAAAAWAAAAAAAAAAAAAAAAAAAAAAHgAQCAAACDzhgAYACALAAgAIAACQCAAAAAAAAAAAAIGIAAACEBYAgCAEQAAHMACQAACYEQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

9.Other Information

Chemical Properties: White to light beige powder

10. Toltal 29 Suppliers View more

Fuao Chemical Technology Co., Ltd.

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Tel: Update Time:2024/11/15

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Henan Tianfu Chemical Co.,Ltd

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Tel: Update Time:2024/11/15

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Dayang Chem (Hangzhou) Co., Ltd.

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Tel: Update Time:2024/06/17

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Alfa Chemistry

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Tel: Update Time:2024/09/23

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Hangzhou KieRay Chem Co., Ltd.

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Tel: Update Time:2024/05/22

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11. Realated Product Infomation