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3-Hydroxy-2-methylpyridine

CAS：1121-25-1
MW:109.12588
MF：C6H7NO

3-Hydroxy-2-methylpyridine, with the chemical formula C6H7NO and CAS registry number 1121-25-1, is a compound known for its presence in various chemical reactions and processes. This compound, also referred to as 3-Hydroxypicoline, is characterized by its hydroxyl and methyl functional groups attached to a pyridine ring. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 3-Hydroxy-2-methylpyridine exhibits a pale yellow color and is typically a liquid at room temperature. It is important to handle this compound with caution due to its potential hazards, including its flammability and toxicity. Overall, 3-Hydroxy-2-methylpyridine plays a significant role in the field of organic chemistry, offering a versatile platform for the development of various chemical compounds.

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Names and ldentifier
Properties
Use and Manufacturing
Safety and Handling
Msds
NMR Spectrum
Other Information
Computational chemical data
Related Questions
Realated Product Infomation

1. Names and Identifiers

1.1 Name: 3-Hydroxy-2-methylpyridine

1.2 Synonyms: 2-Methyl-3-hydroxypyridine; 2-METHYL-3-PYRIDINOL; 2-methylpyridin-3-ol; 3-HYDROXY-2-PICOLINE; 3-Pyridinol, 2-methyl-; 6-Methylpyridin-5-ol; EINECS 214-327-3; MFCD00082538; NSC 27506; Pyridyl-3-methanol;

1.3 CAS No.: 1121-25-1

1.4 CID: 70719

1.5 EINECS: 214-327-3

1.6 Molecular Formula: C6H7NO

1.7 Inchi: InChI=1S/C6H7NO/c1-5-6(8)3-2-4-7-5/h2-4,8H,1H3

1.8 InChkey: AQSRRZGQRFFFGS-UHFFFAOYSA-N

1.9 Canonical Smiles: CC1=C(C=CC=N1)O

1.10 Isomers Smiles: CC1=C(C=CC=N1)O

2. Properties

2.1 Appearance: beige-brown powder

2.2 Storage: Ambient temperatures.

2.3 Chemical Properties: beige-brown powder

2.4 Color/Form: Powder

2.5 pKa: 10.38±0.10(Predicted)

2.6 Water Solubility: Very soluble

2.7 StorageTemp: Store in a cool, dry place. Store in a tightly closed container.

3. Use and Manufacturing

3.1 Description

3-Hydroxy-2-methylpyridine, with the chemical formula C6H7NO, has the CAS number 1121-25-1. It appears as a colorless to light yellow liquid with a strong odor. The basic structure of 3-Hydroxy-2-methylpyridine consists of a pyridine ring with a hydroxyl group and a methyl group attached. This compound is soluble in water. Safety information regarding 3-Hydroxy-2-methylpyridine is not available.

Applicable Fields

Pharmaceuticals: 3-Hydroxy-2-methylpyridine is used in the pharmaceutical industry for various purposes. Its mechanism of action in this field may involve its ability to act as a precursor or intermediate in the synthesis of certain drugs or active pharmaceutical ingredients.

Storage

Conditions: Store in a cool and dry place.

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3.2 Usage: 3-Hydroxy-2-methylpyridine is used in the preparation of substituted pyridine and pyrimidine derivatives and their use in treating viral infections.

4. Safety and Handling

4.1 Safety: Hazard Codes: Xn,Xi
The Risk Statements information of 3-hydroxy-2-methylpyridine:
22: Harmful if swallowed
41: Risk of serious damage to eyes
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of 3-hydroxy-2-methylpyridine:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39: Wear suitable protective clothing, gloves and eye/face protection

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4.2 Specification: General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dangerous fire hazard in the form of dust when exposed to heat or flame.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store 3-Hydroxy-2-methylpyridine (CAS NO.1121-25-1) in a cool, dry place. Store in a tightly closed container.

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5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Skin irritation, Category 2

Serious eye damage, Category 1

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H335 May cause respiratory irritation
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/\u2026 P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

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6. NMR Spectrum

Mass spectrum (electron ionization)

7. Synthesis Route

1121-25-1Total: 25 Synthesis Route

109-06-8 118 Suppliers

1121-25-1 173 Suppliers

154-17-6 280 Suppliers

1121-25-1 173 Suppliers

1072-83-9 164 Suppliers

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8. Precursor and Product

precursor:

1450-49-3

1192-62-7

87440-88-8

2484-55-1

22095-34-7

2168-13-0

67992-22-7

109-06-8

154-17-6

product:

118399-86-3

874-24-8

181633-42-1

72731-33-0

850882-87-0

856165-76-9

200940-27-8

188923-75-3

1849-55-4

848952-39-6

9. Computed Properties

Molecular Weight：109.12588g/mol
Molecular Formula：C₆H₇NO
Compound Is Canonicalized：True
Exact Mass：0.9
XLogP3-AA：109.052763847
Monoisotopic Mass：109.052763847
Complexity：74.9
Rotatable Bond Count：0
Hydrogen Bond Donor Count：1
Hydrogen Bond Acceptor Count：2
Topological Polar Surface Area：33.1
Heavy Atom Count：：8
Defined Atom Stereocenter Count：0
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：1
CACTVS Substructure Key Fingerprint：AAADcYBiIAAAAAAAAAAAAAAAAAAAAAAAAAAsAAAAAAAAAAABgAAAHgAACAAACAzBlgQ+hpIIEgCgATRnRASCgCAxYiAI2CA/bJgKJuLSkZOEcAhkwBHY2AcwAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

10.Other Information

BRN: 107937

Chemical Properties: beige-brown powder

Uses: Used in the preparation of substituted pyridine and pyrimidine derivatives and their use in treating viral infections.

11. Toltal 161 Suppliers View more

Hangzhou Dingyan Chem Co.,Ltd

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Tel: Update Time:2024/11/15

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Hebei Yanxi Chemical Co.,Ltd

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Amitychem Corporation

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Tel: Update Time:2023/06/28

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Hangzhou KieRay Chem Co., Ltd.

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Dayang Chem (Hangzhou) Co., Ltd.

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Tel: Update Time:2024/06/17

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12. Related Questions

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13. Realated Product Infomation