Encyclopedia / Organic Intermediate / Custom Manufacturing

Z-GLY-PRO-OH

CAS：1160-54-9
MW:306.318
MF：C15H18N2O5

Z-GLY-PRO-OH, with the chemical formula C11H15N3O4 and CAS registry number 1160-54-9, is a compound known for its role as a peptide. This compound is a derivative of the amino acids glycine and proline, with an added hydroxyl group. Z-GLY-PRO-OH is commonly used in peptide synthesis and as a building block for the creation of larger peptides. It is also utilized in biochemical research and drug development due to its ability to mimic certain peptide structures and functions. This compound has been studied for its potential therapeutic applications, including its role in modulating cellular processes and as a potential treatment for various diseases. Z-GLY-PRO-OH is a valuable tool in the field of peptide chemistry and continues to be explored for its potential in various scientific and medical applications.

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Names and ldentifier
Properties
Use and Manufacturing
Msds
NMR Spectrum
Other Information
Computational chemical data
Realated Product Infomation

1. Names and Identifiers

1.1 Name: Z-GLY-PRO-OH

1.2 Synonyms: (Benzyloxycarbonyl)glycyl-L-proline; 1-[N-[(phenylmethoxy)carbonyl]glycyl]-L-proline; BENZYLOXYCARBONYLGLYCYL-L-PROLINE; Carbobenzoxyglycyl-L-proline; Cbz-gly-pro-oh; L-Proline, 1-[N-[(phenylmethoxy)carbonyl]glycyl]-; L-Proline, N-[(phenylmethoxy)carbonyl]glycyl-; N-[(Phenylmethoxy)carbonyl]glycyl-L-proline; N-BENZYLOXYCARBONYLGLYCYL-L-PROLINE; N-CARBOBENZOXYGLYCYL-L-PROLINE; NSC 89634; Proline, 1-(N-carboxyglycyl)-, N-benzyl ester, L-; Z-GLYCYL-L-PROLINE; Z-GLY-PRO; Z-GLY-PRO-OH; Z-L-GLYCYL-L-PROLINE;

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1.3 CAS No.: 1160-54-9

1.4 CID: 439540

1.5 EINECS: 214-598-8

1.6 Molecular Formula: C15H18N2O5

1.7 Inchi: InChI=1S/C15H18N2O5/c18-13(17-8-4-7-12(17)14(19)20)9-16-15(21)22-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2,(H,16,21)(H,19,20)/t12-/m0/s1

1.8 InChkey: ZTUKZKYDJMGJDC-LBPRGKRZSA-N

1.9 Canonical Smiles: C1CC(N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)O

1.10 Isomers Smiles: C1C[C@H](N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)O

2. Properties

2.1 Solubility: 微溶 (1.3 g/L) (25 oC),

2.2 Storage: ?20°C

2.3 Color/Form: White to Yellow Solid

2.4 pKa: 3.51±0.20(Predicted)

2.5 StorageTemp: −20°C

3. Use and Manufacturing

3.1 Description

Z-GLY-PRO-OH, with the chemical formula C11H19NO4, has the CAS number 1160-54-9. It appears as a white solid with no distinct odor. The basic structure of Z-GLY-PRO-OH consists of a zwitterionic amino acid, glycylproline, attached to a hydroxyl group. This compound is soluble in water. Z-GLY-PRO-OH is considered to be relatively safe for use. However, as with any chemical, it is important to handle it with care and follow proper safety precautions.

Applicable Fields

Peptide Synthesis: Z-GLY-PRO-OH is commonly used in peptide synthesis. Its purpose in this field is to serve as a building block for the formation of peptides. The mechanism of action involves the coupling of Z-GLY-PRO-OH with other amino acids to create peptide bonds and construct desired peptide sequences.

Biochemical Research: This compound is also utilized in biochemical research. It can be used as a substrate or reagent in various enzymatic reactions or assays. The mechanism of action in this context depends on the specific experiment or study being conducted.

Storage

ConditionsStore in a cool and dry place.

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4. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

no data available

2.2 GHS label elements, including precautionary statements

Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Precautionary statement(s)
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

2.3 Other hazards which do not result in classification

no data available

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5. NMR Spectrum

13C NMR : Predict

1H NMR : Predict

Predict 1H proton NMR

6. Synthesis Route

1160-54-9Total: 14 Synthesis Route

501-53-1 149 Suppliers

1160-54-9 33 Suppliers

147-85-3 620 Suppliers

1160-54-9 33 Suppliers

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7. Precursor and Product

precursor:

66449-90-9

501-53-1

147-85-3

2899-60-7

1138-80-3

67336-99-6

2899-57-2

1738-86-9

65022-15-3

2778-21-4

product:

38417-02-6

2646-63-1

13100-15-7

704-15-4

2441-63-6

8. Computed Properties

Molecular Weight：306.318g/mol
Molecular Formula：C₁₅H₁₈N₂O₅
Compound Is Canonicalized：True
XLogP3-AA：306.12157168
Monoisotopic Mass：306.12157168
Complexity：420
Rotatable Bond Count：6
Hydrogen Bond Donor Count：2
Hydrogen Bond Acceptor Count：5
Topological Polar Surface Area：95.9
Heavy Atom Count：：22
Defined Atom Stereocenter Count：1
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：1
CACTVS Substructure Key Fingerprint：AAADceBzOAAAAAAAAAAAAAAAAAAAAWAAAAAwAAAAAAAAAAABAAAAHgAQCAAADCjhmAYwCIPABgCIAiHSGAACAAAgAAAIiIGICIkKZjKAsTiccAAkxgGYqAeY0SIOAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==