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Bis(4-hydroxyphenyl) Sulfone

CAS：80-09-1
MW:250.2704
MF：C12H10O4S

4,4'-Sulfonyldiphenol is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.

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Names and ldentifier
Properties
Use and Manufacturing
Safety and Handling
Msds
NMR Spectrum
Other Information
Computational chemical data
Related Questions
Realated Product Infomation

1. Names and Identifiers

1.1 Name: Bis(4-hydroxyphenyl) Sulfone

1.2 Synonyms: 4-(4-hydroxyphenyl)sulfonylphenol; 4,4'-DIHYDROXYDIPHENYL SULFONE; 4,4-DIHYDROXYDIPHENYL SULFONE; 4,4-DIHYDROXYDIPHENYL SULPHONE; 4,4'-DIHYDROXYDIPHENYLSULPHONE; 4,4'-SULFONYLDIPHENOL; 4,4'-Sulphonyldiphenol; 4-HYDROXYPHENYL SULFONE; BIS(4-HYDROXYPHENYL) SULPHONE; EINECS 201-250-5; MFCD00002350; Phenol, 4,4'-sulfonylbis-; phenol, 4,4'-sulfonyldi-;

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1.3 CAS No.: 80-09-1

1.4 CID: 6626

1.5 EINECS: 201-250-5

1.6 Molecular Formula: C12H10O4S

1.7 Inchi: InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H

1.8 InChkey: VPWNQTHUCYMVMZ-UHFFFAOYSA-N

1.9 Canonical Smiles: C1=CC(=CC=C1O)S(=O)(=O)C2=CC=C(C=C2)O

1.10 Isomers Smiles: C1=CC(=CC=C1O)S(=O)(=O)C2=CC=C(C=C2)O

2. Properties

2.1 Solubility: 1.1g/l

2.2 Λmax: 295nm(H2O)(lit.)

2.3 Appearance: light yellow crystalline powder

2.4 Storage: Ambient temperatures.

2.5 Chemical Properties: 4,4'-Sulfonyldiphenol is light yellow crystalline powder

2.6 Color/Form: White to grayish-green

2.7 Decomposition: When heated to decomposition it emits toxic fumes of Sulfur oxides.

2.8 PH: 6.6-7.0 (100g/l, H2O, 20℃)

2.9 pKa: 7?+-.0.15(Predicted)

2.10 Water Solubility: 1.1 g/L (20 oC)

2.11 Stability: Stable. Incompatible with strong bases, acid chloride, acid anhydrides, strong oxidizing agents.

2.12 StorageTemp: Store below +30°C.

3. Use and Manufacturing

3.1 Definition: 4,4'-Sulfonyldiphenol is asulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. Bis(4-hydroxyphenyl) SulfoneSupplier

3.2 Description: Bis(4-hydroxyphenyl) Sulfone (CAS 80-09-1) is a chemical compound that is commonly used in various industries. It has a molecular structure consisting of bis(4-hydroxyphenyl) sulfone units, which are connected by sulfur atoms. This compound appears as a white crystalline powder and is insoluble in water. It has a melting point of approximately 220-225°C and a boiling point of around 400°C.

Applicable Fields
Bis(4-hydroxyphenyl) Sulfone has several applications in different fields:

1. Polymer Industry: In the polymer industry, this chemical is used as a monomer in the production of various polymers. It acts as a cross-linking agent, improving the mechanical properties and thermal stability of the polymers. The mechanism of action involves the formation of covalent bonds between the polymer chains, resulting in a stronger and more durable material.

2. Medical Industry: Bis(4-hydroxyphenyl) Sulfone is also used in the medical field. It is a key component in the production of certain types of medical devices, such as dental materials and implants. Its biocompatibility and resistance to high temperatures make it suitable for these applications.

3. Electronics Industry: In the electronics industry, this chemical is utilized as a heat-resistant material. It is commonly used in the production of printed circuit boards (PCBs) and electrical connectors. Its high thermal stability and electrical insulation properties make it ideal for these applications.

Storage Conditions
The storage conditions for Bis(4-hydroxyphenyl) Sulfone are as follows: Store in a cool, dry place, away from direct sunlight.

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3.3 Usage: 4,4'-Sulfonyldiphenol is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.

4. Safety and Handling

4.1 Report: Reported in EPA TSCA Inventory.

4.2 Safety: Safety Information about? 4,4'-Sulfonyldiphenol (CAS NO.80-09-1):
Hazard Codes:?Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36: Wear suitable protective clothing.?
S39: Wear eye / face protection.
WGK Germany: 2
RTECS: SM8925000
HS Code: 29309070
Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of SO_x.?

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4.3 Specification: General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dangerous fire hazard in the form of dust when exposed to heat or flame.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.?
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.

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4.4 Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	skin	> 1mg/kg (1mg/kg)	?	National Technical Information Service. Vol. OTS0534330,
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)	?	National Technical Information Service. Vol. OTS0534330,
mouse	LD50	oral	1600mg/kg (1600mg/kg)	?	National Technical Information Service. Vol. OTS0534330,
rabbit	LD50	skin	> 10250mg/kg (10250mg/kg)	?	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 601-05501, Pg. 1974,
rabbit	LDLo	oral	4700mg/kg (4700mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	National Technical Information Service. Vol. OTS0555048,
rat	LD50	intraperitoneal	400mg/kg (400mg/kg)	?	National Technical Information Service. Vol. OTS0534330,
rat	LD50	oral	4556mg/kg (4556mg/kg)	?	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 601-05501, Pg. 1974,

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5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s)	No symbol.
Signal word	No signal word.
Hazard statement(s)	none
Precautionary statement(s)
Prevention	none
Response	none
Storage	none
Disposal	none

2.3 Other hazards which do not result in classification

none

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6. NMR Spectrum

13C NMR : DMSO-d6

1H NMR : 400 MHz in DMSO-d6

1H NMR : 90 MHz in DMSO-d6

IR : KBr disc

Mass

7. Synthesis Route

80-09-1Total: 38 Synthesis Route

80-07-9 112 Suppliers

80-09-1 168 Suppliers

80-08-0 304 Suppliers

80-09-1 168 Suppliers

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8. Precursor and Product

precursor:

100-66-3

80-08-0

103-73-1

69-72-7

95-48-7

98-67-9

108-95-2

80-07-9

98-48-6

product:

383-29-9

7149-20-4

39635-79-5

7019-01-4

77-46-3

80-08-0

80-00-2

7545-50-8

80-07-9

127-63-9

9. Computed Properties

Molecular Weight：250.2704g/mol
Molecular Formula：C₁₂H₁₀O₄S
Compound Is Canonicalized：True
XLogP3-AA：250.02997997
Monoisotopic Mass：250.02997997
Complexity：302
Rotatable Bond Count：2
Hydrogen Bond Donor Count：2
Hydrogen Bond Acceptor Count：4
Topological Polar Surface Area：83
Heavy Atom Count：：17
Defined Atom Stereocenter Count：0
Undefined Atom Stereocenter Count：0
Defined Bond Stereocenter Count：0
Undefined Bond Stereocenter Count：0
Isotope Atom Count：0
Covalently-Bonded Unit Count：1
CACTVS Substructure Key Fingerprint：AAADccBwOABAAAAAAAAAAAAAAAAAAAAAAAAwYAAAAAAAAAABQAAAGgQACAAACASA0AAwB4AAAgqAACBCAHBCAAAgKBAIiBgGCIgIJiKiERKAcAAkwBEomAeAQAAAAIAAAAAAAAABAAAAAAAAAAAAAAAAAA==

10.Other Information

Usage: It is a reactant used in epoxy reactions.

BRN: 2052954

Chemical Properties: 4,4'-Sulfonyldiphenol is light yellow crystalline powder

Uses: 4,4'-Sulfonyldiphenol is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.

Definition: 4,4'-Sulfonyldiphenol is a sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.

General Description: Bisphenol S (BPS), belonging to the class of bisphenols, is a structural analog of bisphenol A (BPA), used in a variety of industrial applications and products marketed as BPA-free. It is commonly identified in food and beverages, environmental samples, biological matrices, etc. It is also reported to be used in the production of epoxy resins. BPS is also found to be stable compared to BPA at elevated temperature and sunlight conditions.

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11. Toltal 152 Suppliers View more

Hebei Mojin Biotechnology Co.,Ltd

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Wuhan Fortuna Chemical Co., Ltd.

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Baoji Guokang Healthchem co.,ltd

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Jinlan Pharm-Drugs Technology Co., Limited

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China factory supply Bis(4-hydroxyphenyl) Sulfone CAS NO 80-09-1

Hebei Crovell Biotech Co. Ltd

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12. Related Questions

: What are the potential toxic effects and reproductive disruptions caused by bis(4-hydroxyphenyl) sulfone?General Description Recent scientific research has uncovered the harmful effects of bis(4-hydroxyphenyl) sulfone, a commonly used compound. This study reveals that when cells are exposed to bis(4-hydr..; How to Prepare Bis(4-hydroxyphenyl) Sulfone with High Purity?Currently, the synthesis of Bis(4-hydroxyphenyl) Sulfone in the industry mostly involves the reaction of phenol and concentrated sulfuric acid in a certain solvent. The crude product obtained from the..; What are the harmful effects of Bis(4-hydroxyphenyl) Sulfone on the human body?Bisphenol S is now used as a replacement for bisphenol A and is an additive in polycarbonate plastic (PC). Its transparency and ductility are better. Bis (4- hydroxyphenyl) Sulfone figure. Existing re..; Is Bis(4-hydroxyphenyl) Sulfone in Plastic as Harmful as Bisphenol A?A recent study suggests that Bis(4-hydroxyphenyl) Sulfone in plastic may have similar harmful effects to Bisphenol A. The University of California, Los Angeles (UCLA) has conducted a groundbreaking re..

13. Realated Product Infomation